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HDAC8 histone deacetylase 8 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100662291, updated on 11-Apr-2024

Summary

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Gene symbol
HDAC8
Gene description
histone deacetylase 8
See related
EnsemblRapid:ENSLAFG00000008515
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) X NC_087369.1 (82016744..82324644, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573444.1 (29640277..29952248)

Chromosome X - NC_087369.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135228962 Neighboring gene ribosomal protein S4 X-linked Neighboring gene Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1 Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene large ribosomal subunit protein uL6-like Neighboring gene phosphorylase kinase regulatory subunit alpha 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone deacetylase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone deacetylase 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087369.1 Reference mLoxAfr1.hap2

    Range
    82016744..82324644 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003412724.4 → XP_003412772.1  histone deacetylase 8 isoform X4

    UniProtKB/TrEMBL
    G3T1Y9
    Related
    ENSLAFP00000033548.1, ENSLAFT00000053651.1
    Conserved Domains (1) summary
    cd10000
    Location:16 → 377
    HDAC8; Histone deacetylase 8 (HDAC8)

  2. XM_023551435.2 → XP_023407203.1  histone deacetylase 8 isoform X1

    Conserved Domains (1) summary
    cd10000
    Location:16 → 371
    HDAC8; Histone deacetylase 8 (HDAC8)

  3. XM_064278557.1 → XP_064134627.1  histone deacetylase 8 isoform X3

    Related
    ENSLAFP00000007147.5, ENSLAFT00000008514.5

  4. XM_023551436.2 → XP_023407204.1  histone deacetylase 8 isoform X2

    Related
    ENSLAFP00000046675.1, ENSLAFT00000050520.1
    Conserved Domains (1) summary
    cd10000
    Location:16 → 373
    HDAC8; Histone deacetylase 8 (HDAC8)

  5. XM_064278559.1 → XP_064134629.1  histone deacetylase 8 isoform X6

    Related
    ENSLAFP00000041215.1, ENSLAFT00000038733.1

  6. XM_064278561.1 → XP_064134631.1  histone deacetylase 8 isoform X7

  7. XM_023551437.2 → XP_023407205.1  histone deacetylase 8 isoform X5

    Conserved Domains (1) summary
    cd10000
    Location:16 → 335
    HDAC8; Histone deacetylase 8 (HDAC8)

  8. XM_064278560.1 → XP_064134630.1  histone deacetylase 8 isoform X6

  9. XM_023551438.2 → XP_023407206.1  histone deacetylase 8 isoform X9

    Related
    ENSLAFP00000046757.1, ENSLAFT00000039364.1
    Conserved Domains (1) summary
    cl17011
    Location:16 → 246
    Arginase_HDAC; Arginase-like and histone-like hydrolases

  10. XM_010592715.3 → XP_010591017.1  histone deacetylase 8 isoform X8

    Conserved Domains (1) summary
    cl17011
    Location:16 → 246
    Arginase_HDAC; Arginase-like and histone-like hydrolases

RNA

  1. XR_010319804.1 RNA Sequence

  2. XR_010319803.1 RNA Sequence

  3. XR_010319805.1 RNA Sequence

Nucleotide Protein
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