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PAK4 p21 (RAC1) activated kinase 4 [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100661100, updated on 11-Apr-2024

Summary

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Gene symbol
PAK4
Gene description
p21 (RAC1) activated kinase 4
See related
EnsemblRapid:ENSLAFG00000005252
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 11 NC_087352.1 (4126031..4177459)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573519.1 (2385262..2436733)

Chromosome 11 - NC_087352.1Genomic Context describing neighboring genes Neighboring gene F-box only protein 27-like Neighboring gene acid phosphatase 7, tartrate resistant (putative) Neighboring gene NCCRP1, F-box associated domain containing Neighboring gene interferon lambda-3-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087352.1 Reference mLoxAfr1.hap2

    Range
    4126031..4177459
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010600322.3 → XP_010598624.2  serine/threonine-protein kinase PAK 4

  2. XM_010600323.3 → XP_010598625.2  serine/threonine-protein kinase PAK 4

    Related
    ENSLAFP00000004398.4, ENSLAFT00000005252.4

  3. XM_064293626.1 → XP_064149696.1  serine/threonine-protein kinase PAK 4

  4. XM_064293627.1 → XP_064149697.1  serine/threonine-protein kinase PAK 4

  5. XM_010600324.3 → XP_010598626.1  serine/threonine-protein kinase PAK 4

    See identical proteins and their annotated locations for XP_010598626.1

    UniProtKB/TrEMBL
    G3SVV4
    Conserved Domains (3) summary
    smart00220
    Location:313 → 559
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd01093
    Location:10 → 48
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cl21453
    Location:287 → 578
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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