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UBE2K ubiquitin conjugating enzyme E2 K [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100660572, updated on 11-Apr-2024

Summary

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Gene symbol
UBE2K
Gene description
ubiquitin conjugating enzyme E2 K
See related
EnsemblRapid:ENSLAFG00000007163
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 5 NC_087346.1 (118198126..118260602, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573438.1 (42615673..42678818)

Chromosome 5 - NC_087346.1Genomic Context describing neighboring genes Neighboring gene NEDD4 binding protein 2 Neighboring gene PDS5 cohesin associated factor A Neighboring gene small integral membrane protein 14 Neighboring gene UDP-glucose 6-dehydrogenase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin conjugating enzyme activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein polyubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin-conjugating enzyme E2 K

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087346.1 Reference mLoxAfr1.hap2

    Range
    118198126..118260602 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023549804.2 → XP_023405572.1  ubiquitin-conjugating enzyme E2 K isoform X2

    Related
    ENSLAFP00000035258.1, ENSLAFT00000047606.1
    Conserved Domains (2) summary
    smart00212
    Location:22 → 103
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic domain homologues
    cl21463
    Location:112 → 149
    UBA_like_SF; UBA domain-like superfamily

  2. XM_010591425.3 → XP_010589727.1  ubiquitin-conjugating enzyme E2 K isoform X1

    See identical proteins and their annotated locations for XP_010589727.1

    UniProtKB/TrEMBL
    G3SZH9, G3TZH0
    Related
    ENSLAFP00000020978.2, ENSLAFT00000030864.2
    Conserved Domains (2) summary
    cd00195
    Location:6 → 149
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
    cd14390
    Location:163 → 200
    UBA_II_E2_UBE2K; UBA domain of vertebrate ubiquitin-conjugating enzyme E2 K (UBE2K)
Nucleotide Protein
Heading Accession and Version

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