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PCOLCE procollagen C-endopeptidase enhancer [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100659210, updated on 11-Apr-2024

Summary

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Gene symbol
PCOLCE
Gene description
procollagen C-endopeptidase enhancer
See related
EnsemblRapid:ENSLAFG00000016981
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) 12 NC_087353.1 (88136060..88140985)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573572.1 (303241..308167, complement)

Chromosome 12 - NC_087353.1Genomic Context describing neighboring genes Neighboring gene Sin3A associated protein 25 Neighboring gene leucine rich repeats and calponin homology domain containing 4 Neighboring gene F-box protein 24 Neighboring gene motile sperm domain containing 3 Neighboring gene transferrin receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables collagen binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptidase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in collagen-containing extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
procollagen C-endopeptidase enhancer 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087353.1 Reference mLoxAfr1.hap2

    Range
    88136060..88140985
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003422511.4 → XP_003422559.1  procollagen C-endopeptidase enhancer 1

    UniProtKB/TrEMBL
    G3TI02
    Related
    ENSLAFP00000014239.4, ENSLAFT00000016984.4
    Conserved Domains (2) summary
    cd00041
    Location:159 → 272
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd03576
    Location:338 → 457
    NTR_PCOLCE; NTR domain, PCOLCE subfamily; Procollagen C-endopeptidase enhancers (PCOLCEs) are extracellular matrix proteins that enhance the activity of procollagen C-proteases, by binding to the procollagen I C-peptide. They contain a C-terminal NTR domain, which ...
Nucleotide Protein
Heading Accession and Version

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