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TMLHE trimethyllysine hydroxylase, epsilon [ Loxodonta africana (African savanna elephant) ]

Gene ID: 100658531, updated on 11-Apr-2024

Summary

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Gene symbol
TMLHE
Gene description
trimethyllysine hydroxylase, epsilon
See related
EnsemblRapid:ENSLAFG00000011892
Gene type
protein coding
RefSeq status
MODEL
Organism
Loxodonta africana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: X
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_04 current mLoxAfr1.hap2 (GCF_030014295.1) X NC_087369.1 (178149071..178302416, complement)
102 previous assembly Loxafr3.0 (GCF_000001905.1) Unplaced Scaffold NW_003573540.1 (393482..545507)

Chromosome X - NC_087369.1Genomic Context describing neighboring genes Neighboring gene coagulation factor VIII associated 1 Neighboring gene histone H2A-Bbd type 2/3-like Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene sprouty RTK signaling antagonist 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables trimethyllysine dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carnitine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
trimethyllysine dioxygenase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030014295.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mLoxAfr1.hap2

Genomic

  1. NC_087369.1 Reference mLoxAfr1.hap2

    Range
    178149071..178302416 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064277833.1 → XP_064133903.1  trimethyllysine dioxygenase, mitochondrial isoform X2

  2. XM_064277834.1 → XP_064133904.1  trimethyllysine dioxygenase, mitochondrial isoform X3

  3. XM_064277838.1 → XP_064133908.1  trimethyllysine dioxygenase, mitochondrial isoform X5

  4. XM_064277839.1 → XP_064133909.1  trimethyllysine dioxygenase, mitochondrial isoform X6

  5. XM_064277841.1 → XP_064133911.1  trimethyllysine dioxygenase, mitochondrial isoform X7

  6. XM_064277840.1 → XP_064133910.1  trimethyllysine dioxygenase, mitochondrial isoform X7

  7. XM_003421742.3 → XP_003421790.1  trimethyllysine dioxygenase, mitochondrial isoform X4

    UniProtKB/TrEMBL
    G3T8D4
    Related
    ENSLAFP00000035978.1, ENSLAFT00000042178.1
    Conserved Domains (3) summary
    cd00250
    Location:142 → 408
    CAS_like; Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases ...
    TIGR02410
    Location:70 → 419
    carnitine_TMLD; trimethyllysine dioxygenase
    cl01414
    Location:54 → 133
    DUF971; Protein of unknown function (DUF971)

  8. XM_064277831.1 → XP_064133901.1  trimethyllysine dioxygenase, mitochondrial isoform X1

  9. XM_064277836.1 → XP_064133906.1  trimethyllysine dioxygenase, mitochondrial isoform X4

  10. XM_064277830.1 → XP_064133900.1  trimethyllysine dioxygenase, mitochondrial isoform X1

  11. XM_064277835.1 → XP_064133905.1  trimethyllysine dioxygenase, mitochondrial isoform X4

Nucleotide Protein
Heading Accession and Version

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