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DVL2 dishevelled segment polarity protein 2 [ Sus scrofa (pig) ]

Gene ID: 100625452, updated on 8-Mar-2024

Summary

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Official Symbol
DVL2provided by VGNC
Official Full Name
dishevelled segment polarity protein 2provided by VGNC
Primary source
VGNC:VGNC:87491
See related
Ensembl:ENSSSCG00000025689
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in heart (RPKM 34.9), ovary (RPKM 25.2) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
15
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (52581687..52590266, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 3 NC_010445.3 (139857220..139865809, complement)

Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene discs large MAGUK scaffold protein 4 Neighboring gene acyl-CoA dehydrogenase very long chain Neighboring gene microRNA mir-324 Neighboring gene PHD finger protein 23 Neighboring gene GABA type A receptor-associated protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables frizzled binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2
Names
dishevelled, dsh homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

    Range
    52581687..52590266 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003354942.4 → XP_003354990.2  LOW QUALITY PROTEIN: segment polarity protein dishevelled homolog DVL-2

    UniProtKB/TrEMBL
    A0A4X1V2J0
    Related
    ENSSSCP00000044243.2, ENSSSCT00000064917.3
    Conserved Domains (5) summary
    smart00021
    Location:13 → 93
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:265 → 352
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:424 → 507
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:123 → 263
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:515 → 726
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal
Nucleotide Protein
Heading Accession and Version

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