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GABRA2 gamma-aminobutyric acid type A receptor subunit alpha2 [ Sus scrofa (pig) ]

Gene ID: 100622617, updated on 8-Mar-2024

Summary

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Official Symbol
GABRA2provided by VGNC
Official Full Name
gamma-aminobutyric acid type A receptor subunit alpha2provided by VGNC
Primary source
VGNC:VGNC:88301
See related
Ensembl:ENSSSCG00000028922
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Low expression observed in reference dataset See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 8 NC_010450.4 (36344633..36474840, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 8 NC_010450.3 (38215163..38344937, complement)

Chromosome 8 - NC_010450.4Genomic Context describing neighboring genes Neighboring gene kinesin-like protein KIF3C Neighboring gene uncharacterized LOC110262082 Neighboring gene gamma-aminobutyric acid type A receptor subunit gamma1 Neighboring gene cytochrome c oxidase subunit 7B2, mitochondrial Neighboring gene gamma-aminobutyric acid type A receptor subunit alpha4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GABA-A receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GABA-gated chloride ion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables benzodiazepine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables inhibitory extracellular ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in gamma-aminobutyric acid signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic transmission, GABAergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of GABA-A receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendrite membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-aminobutyric acid receptor subunit alpha-2
Names
gamma-aminobutyric acid type A receptor alpha2 subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010450.4 Reference Sscrofa11.1 Primary Assembly

    Range
    36344633..36474840 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005666628.3 → XP_005666685.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X2

    UniProtKB/TrEMBL
    A0A4X1ULS5, A0A4X1ULV0, A0A5G2R7L6, A0A8D0W0Z4
    Related
    ENSSSCP00000073242.1, ENSSSCT00000069611.2
    Conserved Domains (3) summary
    TIGR00860
    Location:14 → 500
    LIC; Cation transporter family protein
    pfam02931
    Location:43 → 250
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:257 → 497
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  2. XM_013978645.2 → XP_013834099.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X5

    UniProtKB/TrEMBL
    A0A8D1B5M6, A0A8D1EL79
    Conserved Domains (2) summary
    pfam02931
    Location:1 → 166
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:173 → 413
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  3. XM_013978643.2 → XP_013834097.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X1

    UniProtKB/TrEMBL
    A0A4X1ULS5
    Conserved Domains (3) summary
    TIGR00860
    Location:21 → 507
    LIC; Cation transporter family protein
    pfam02931
    Location:50 → 257
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:264 → 504
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  4. XM_013978644.2 → XP_013834098.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X3

    UniProtKB/TrEMBL
    A0A4X1ULS5
    Conserved Domains (3) summary
    TIGR00860
    Location:21 → 447
    LIC; Cation transporter family protein
    pfam02931
    Location:50 → 257
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:264 → 444
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  5. XM_021101165.1 → XP_020956824.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A4X1ULS5, A0A4X1ULU0, A0A8D1GXH7, I3L720
    Related
    ENSSSCP00000019824.2, ENSSSCT00000023000.4
    Conserved Domains (1) summary
    cl27321
    Location:14 → 440
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain

  6. XM_021101166.1 → XP_020956825.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X4

    UniProtKB/TrEMBL
    A0A4X1ULS5, A0A4X1ULU0, A0A8D1GXH7, I3L720
    Conserved Domains (1) summary
    cl27321
    Location:14 → 440
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
Nucleotide Protein
Heading Accession and Version

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