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EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100604860, updated on 8-Mar-2024

Summary

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Gene symbol
EZH1
Gene description
enhancer of zeste 1 polycomb repressive complex 2 subunit
See related
EnsemblRapid:ENSNLEG00000011781
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) Unplaced Scaffold NW_022095770.1 (516446..563114)
102 previous assembly Nleu_3.0 (GCF_000146795.2) Unplaced Scaffold NW_003501569.1 (1621393..1649836, complement)

NW_022095770.1Genomic Context describing neighboring genes Neighboring gene receptor activity modifying protein 2 Neighboring gene non-histone chromosomal protein HMG-17 pseudogene Neighboring gene contactin associated protein 1 Neighboring gene C-C motif chemokine receptor 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K27 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone-lysine N-methyltransferase EZH1
Names
enhancer of zeste homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NW_022095770.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    516446..563114
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030808329.1 → XP_030664189.1  histone-lysine N-methyltransferase EZH1 isoform X1

    UniProtKB/TrEMBL
    G1RM60
    Related
    ENSNLEP00000014324.4, ENSNLET00000015032.4
    Conserved Domains (5) summary
    COG2940
    Location:463 → 727
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    cd00167
    Location:433 → 474
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    cd19217
    Location:608 → 743
    SET_EZH1; SET domain found in enhancer of zeste homolog 1 (EZH1) and similar proteins
    pfam11616
    Location:39 → 68
    EZH2_WD-Binding; WD repeat binding protein EZH2
    pfam18118
    Location:159 → 262
    PRC2_HTH_1; Polycomb repressive complex 2 tri-helical domain

  2. XM_030808331.1 → XP_030664191.1  histone-lysine N-methyltransferase EZH1 isoform X2

    UniProtKB/TrEMBL
    G1RM60
    Related
    ENSNLEP00000043672.2, ENSNLET00000040795.2
    Conserved Domains (5) summary
    COG2940
    Location:423 → 687
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    cd00167
    Location:393 → 434
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    cd19217
    Location:568 → 703
    SET_EZH1; SET domain found in enhancer of zeste homolog 1 (EZH1) and similar proteins
    pfam11616
    Location:39 → 68
    EZH2_WD-Binding; WD repeat binding protein EZH2
    pfam18118
    Location:119 → 222
    PRC2_HTH_1; Polycomb repressive complex 2 tri-helical domain

  3. XM_030808330.1 → XP_030664190.1  histone-lysine N-methyltransferase EZH1 isoform X1

    UniProtKB/TrEMBL
    G1RM60
    Conserved Domains (5) summary
    COG2940
    Location:463 → 727
    SET; SET domain-containing protein (function unknown) [General function prediction only]
    cd00167
    Location:433 → 474
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    cd19217
    Location:608 → 743
    SET_EZH1; SET domain found in enhancer of zeste homolog 1 (EZH1) and similar proteins
    pfam11616
    Location:39 → 68
    EZH2_WD-Binding; WD repeat binding protein EZH2
    pfam18118
    Location:159 → 262
    PRC2_HTH_1; Polycomb repressive complex 2 tri-helical domain
Nucleotide Protein
Heading Accession and Version

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