U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

IL6R interleukin 6 receptor [ Nomascus leucogenys (northern white-cheeked gibbon) ]

Gene ID: 100604063, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
IL6R
Gene description
interleukin 6 receptor
See related
EnsemblRapid:ENSNLEG00000033170
Gene type
protein coding
RefSeq status
MODEL
Organism
Nomascus leucogenys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 12
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Asia_NLE_v1 (GCF_006542625.1) 12 NC_044392.1 (46762490..46826312, complement)
102 previous assembly Nleu_3.0 (GCF_000146795.2) 12 NC_019827.1 (47709711..47752867, complement)

Chromosome 12 - NC_044392.1Genomic Context describing neighboring genes Neighboring gene tudor domain containing 10 Neighboring gene Src homology 2 domain containing E Neighboring gene 26S proteasome non-ATPase regulatory subunit 8 pseudogene Neighboring gene 40S ribosomal protein SA-like Neighboring gene U7 small nuclear RNA Neighboring gene ATPase phospholipid transporting 8B2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables interleukin-11 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-11 receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-6 binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interleukin-6-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of activation of Janus kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
interleukin-6 receptor subunit alpha

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Asia_NLE_v1 Primary Assembly

Genomic

  1. NC_044392.1 Reference Asia_NLE_v1 Primary Assembly

    Range
    46762490..46826312 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030824405.1 → XP_030680265.1  interleukin-6 receptor subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A2I3GWN3
    Related
    ENSNLEP00000035711.2, ENSNLET00000034112.2
    Conserved Domains (3) summary
    smart00408
    Location:39 → 97
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:216 → 308
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09240
    Location:118 → 213
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding

  2. XM_030824406.1 → XP_030680266.1  interleukin-6 receptor subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A2I3GFY0
    Related
    ENSNLEP00000030215.2, ENSNLET00000039371.2
    Conserved Domains (3) summary
    smart00408
    Location:39 → 97
    IGc2; Immunoglobulin C-2 Type
    cd00063
    Location:216 → 308
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam09240
    Location:118 → 213
    IL6Ra-bind; Interleukin-6 receptor alpha chain, binding
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.