TRIM34 tripartite motif containing 34 [Pan troglodytes (chimpanzee)] - Gene

Summary

Official Symbol: TRIM34provided by VGNC
Official Full Name: tripartite motif containing 34provided by VGNC
Primary source: VGNC:VGNC:110040
Locus tag: CK820_G0005948
See related: Ensembl:ENSPTRG00000003257
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Pan troglodytes
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs: human all
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Genomic context

Location:: chromosome: 11

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2)	9	NC_072407.2 (9768755..9793563)
RS_2023_04	previous assembly	NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1)	11	NC_072409.1 (9662414..9685286)

Chromosome 9 - NC_072407.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Markers

ECD13910 (e-PCR)
- UniSTS:294935

ECD15519 (e-PCR)
- UniSTS:296536

REN98993 (e-PCR)
- UniSTS:423790

REN99039 (e-PCR)
- UniSTS:423836

REN99040 (e-PCR)
- UniSTS:423837

REN99041 (e-PCR)
- UniSTS:423838

REN99042 (e-PCR)
- UniSTS:423839

REN99043 (e-PCR)
- UniSTS:423840

stSG611128 (e-PCR)
- UniSTS:449232

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info	PubMed
enables protein kinase binding	IEA Inferred from Electronic Annotation more info	PubMed
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info	PubMed
enables zinc ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in positive regulation of NF-kappaB transcription factor activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of autophagy	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of canonical NF-kappaB signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein polyubiquitination	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of protein localization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of viral entry into host cell	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase TRIM34

NP_001192106.1

EC 2.3.2.27

XP_016775228.1

EC 2.3.2.27

XP_054517002.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001205177.1 → NP_001192106.1 E3 ubiquitin-protein ligase TRIM34

See identical proteins and their annotated locations for NP_001192106.1

Status: VALIDATED

Source sequence(s)

JAQQLN020000009

UniProtKB/TrEMBL

A0A2J8P6P2, A0A6D2XXR9, H2Q303

Related

ENSPTRP00000005727.6, ENSPTRT00000006206.7

Conserved Domains (3) summary

cd15825
Location:300 → 485

SPRY_PRY_TRIM34; PRY/SPRY domain in tripartite motif-containing protein 34 (TRIM34), also known as RING finger protein 21 (RNF21) or interferon-responsive finger protein (IFP1)

cd16591
Location:12 → 61

RING-HC_TRIM5_like-C-IV; RING finger, HC subclass, found in tripartite motif-containing proteins TRIM5, TRIM6, TRIM22, TRIM34 and similar proteins

cd19761
Location:95 → 134

Bbox2_TRIM5-like; B-box-type 2 zinc finger found in tripartite motif-containing proteins, TRIM5, TRIM6, TRIM22, TRIM34, TRIM38 and similar proteins

RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Genomic

NC_072407.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

Range

9768755..9793563

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054661027.2 → XP_054517002.1 E3 ubiquitin-protein ligase TRIM34 isoform X1

UniProtKB/TrEMBL

A0A2J8P6P2, A0A6D2XXR9, H2Q303
XM_016919739.4 → XP_016775228.1 E3 ubiquitin-protein ligase TRIM34 isoform X2