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sox10 SRY-box transcription factor 10 [ Oreochromis niloticus (Nile tilapia) ]

Gene ID: 100534551, updated on 8-Mar-2024

Summary

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Gene symbol
sox10
Gene description
SRY-box transcription factor 10
See related
Ensembl:ENSONIG00000037001
Gene type
protein coding
RefSeq status
MODEL
Organism
Oreochromis niloticus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Cichlomorphae; Cichliformes; Cichlidae; African cichlids; Pseudocrenilabrinae; Oreochromini; Oreochromis
Also known as
SOX10b
Expression
Biased expression in brain (RPKM 9.1), eye (RPKM 7.6) and 4 other tissues See more
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG4
Exon count:
4
Annotation release Status Assembly LG Location
104 current O_niloticus_UMD_NMBU (GCF_001858045.2) LG4 NC_031969.2 (9917485..9926026, complement)
103 previous assembly ASM185804v2 (GCF_001858045.1) LG4 NC_031969.1 (28381194..28389743)

Linkage Group LG4 - NC_031969.2Genomic Context describing neighboring genes Neighboring gene MICAL-like protein 1 Neighboring gene RNA polymerase II, I and III subunit F Neighboring gene ATP-sensitive inward rectifier potassium channel 12 Neighboring gene GTPase IMAP family member 4 Neighboring gene KDEL endoplasmic reticulum protein retention receptor 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Oreochromis niloticus Transcriptome or Gene expression
  • Description: Oreochromis niloticus (Nile Tilapia) RNA sequencing from multiple tissues.
  • BioProject: PRJNA78915
  • Analysis date: Fri Dec 29 00:23:36 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in enteric nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in morphogenesis of an epithelium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neural crest cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peripheral nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor SOX-10
Names
SRY-box 10
transcription factor sox10

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oreochromis niloticus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference O_niloticus_UMD_NMBU Primary Assembly

Genomic

  1. NC_031969.2 Reference O_niloticus_UMD_NMBU Primary Assembly

    Range
    9917485..9926026 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005468427.4 → XP_005468484.1  transcription factor SOX-10 isoform X1

    Conserved Domains (2) summary
    cd01388
    Location:106 → 176
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    pfam12444
    Location:13 → 96
    Sox_N; Sox developmental protein N terminal

  2. XM_005468428.4 → XP_005468485.1  transcription factor SOX-10 isoform X2

    UniProtKB/TrEMBL
    A0A669BRA5
    Related
    ENSONIP00000038269.1, ENSONIT00000036644.1
    Conserved Domains (2) summary
    cd01388
    Location:106 → 176
    SOX-TCF_HMG-box; SOX-TCF_HMG-box, class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and ...
    pfam12444
    Location:13 → 96
    Sox_N; Sox developmental protein N terminal
Nucleotide Protein
Heading Accession and Version

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