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nf1 neurofibromin 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100493879, updated on 8-Mar-2024

Summary

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Official Symbol
nf1provided by Xenbase
Official Full Name
neurofibromin 1provided by Xenbase
Primary source
Xenbase:XB-GENE-488024
See related
Ensembl:ENSXETG00000021350
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs
human mouse all
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Genomic context

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See nf1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
59
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (104648662..104787963, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 2 NC_030678.1 (101035247..101173304, complement)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene musashi RNA binding protein 2 Neighboring gene uncharacterized LOC116408862 Neighboring gene A-kinase anchoring protein 1 Neighboring gene ecotropic viral integration site 2A Neighboring gene ecotropic viral integration site 2B Neighboring gene oligodendrocyte myelin glycoprotein Neighboring gene uncharacterized LOC116408863 Neighboring gene WD repeat and SOCS box containing 1 Neighboring gene kinase suppressor of ras 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
neurofibromin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    104648662..104787963 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012957569.3 → XP_012813023.1  neurofibromin isoform X3

    UniProtKB/TrEMBL
    A0A6I8R1J3, A0A6I8SSQ7
    Related
    ENSXETP00000101339.2, ENSXETT00000072130.2
    Conserved Domains (3) summary
    cd05130
    Location:1143 → 1475
    RasGAP_Neurofibromin; Ras-GTPase Activating Domain of neurofibromin
    cd13313
    Location:1652 → 1761
    PH_NF1; Neurofibromin-1 Pleckstrin homology-like domain
    pfam13716
    Location:1526 → 1660
    CRAL_TRIO_2; Divergent CRAL/TRIO domain

  2. XM_002936819.5 → XP_002936865.2  neurofibromin isoform X1

    UniProtKB/TrEMBL
    A0A6I8R1J3, A0A8J0QMR5
    Conserved Domains (3) summary
    cd05130
    Location:1143 → 1496
    RasGAP_Neurofibromin; Ras-GTPase Activating Domain of neurofibromin
    cd13313
    Location:1673 → 1782
    PH_NF1; Neurofibromin-1 Pleckstrin homology-like domain
    pfam13716
    Location:1547 → 1681
    CRAL_TRIO_2; Divergent CRAL/TRIO domain

  3. XM_018091613.2 → XP_017947102.1  neurofibromin isoform X4

    UniProtKB/TrEMBL
    A0A6I8R1J3, A0A6I8SBJ8
    Related
    ENSXETP00000094322.2, ENSXETT00000087450.2
    Conserved Domains (3) summary
    cd05130
    Location:1143 → 1496
    RasGAP_Neurofibromin; Ras-GTPase Activating Domain of neurofibromin
    cd13313
    Location:1673 → 1782
    PH_NF1; Neurofibromin-1 Pleckstrin homology-like domain
    pfam13716
    Location:1547 → 1681
    CRAL_TRIO_2; Divergent CRAL/TRIO domain

  4. XM_018091610.2 → XP_017947099.1  neurofibromin isoform X2

    UniProtKB/TrEMBL
    A0A6I8R7X8, A0A8J0SYM5
    Related
    ENSXETP00000078021.2, ENSXETT00000084477.2
Nucleotide Protein Strain
Heading Accession and Version

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