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flt4 fms related tyrosine kinase 4 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100493801, updated on 25-Jan-2024

Summary

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Official Symbol
flt4provided by Xenbase
Official Full Name
fms related tyrosine kinase 4provided by Xenbase
Primary source
Xenbase:XB-GENE-483183
See related
Ensembl:ENSXETG00000008399
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
flt-4; vegfr3; vegfr-3
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Genomic context

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See flt4 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
30
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (20149932..20265893)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (9748160..9864540)

Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene nucleophosmin (nucleolar phosphoprotein B23, numatrin) Neighboring gene solute carrier family 23 member 1 Neighboring gene E3 ubiquitin-protein ligase RNF130-like Neighboring gene uncharacterized LOC116409701 Neighboring gene uncharacterized LOC105946024

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within angiogenesis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
vascular endothelial growth factor receptor 3
XP_012815191.1
XP_012815193.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    20149932..20265893
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012959739.2 → XP_012815193.1  vascular endothelial growth factor receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A6I8SUR9, A0A8J0SJK9
    Conserved Domains (7) summary
    smart00408
    Location:712 → 774
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:583 → 678
    IG; Immunoglobulin
    smart00410
    Location:349 → 430
    IG_like; Immunoglobulin like
    pfam07679
    Location:697 → 784
    I-set; Immunoglobulin I-set domain
    cd05102
    Location:856 → 1191
    PTKc_VEGFR3; Catalytic domain of the Protein Tyrosine Kinase, Vascular Endothelial Growth Factor Receptor 3
    pfam07714
    Location:864 → 1184
    Pkinase_Tyr; Protein tyrosine kinase
    cl11960
    Location:252 → 336
    Ig; Immunoglobulin domain

  2. XM_012959737.2 → XP_012815191.1  vascular endothelial growth factor receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A6I8RMQ8, A0A6I8SUR9
    Related
    ENSXETP00000082710.2, ENSXETT00000079756.2
    Conserved Domains (5) summary
    smart00408
    Location:712 → 774
    IGc2; Immunoglobulin C-2 Type
    cd05102
    Location:856 → 1191
    PTKc_VEGFR3; Catalytic domain of the Protein Tyrosine Kinase, Vascular Endothelial Growth Factor Receptor 3
    pfam13927
    Location:579 → 676
    Ig_3; Immunoglobulin domain
    pfam17988
    Location:789 → 823
    VEGFR-2_TMD; VEGFR-2 Transmembrane domain
    cl11960
    Location:252 → 337
    Ig; Immunoglobulin domain
Nucleotide Protein Strain
Heading Accession and Version

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