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ntrk1 neurotrophic receptor tyrosine kinase 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100489637, updated on 8-Mar-2024

Summary

Official Symbol
ntrk1provided by Xenbase
Official Full Name
neurotrophic receptor tyrosine kinase 1provided by Xenbase
Primary source
Xenbase:XB-GENE-923001
See related
Ensembl:ENSXETG00000018040
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
TrkA; trk1
Orthologs
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Genomic context

Location:
chromosome: 8
Exon count:
17
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 8 NC_030684.2 (131628758..131707039)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 8 NC_030684.1 (110249225..110320405)

Chromosome 8 - NC_030684.2Genomic Context describing neighboring genes Neighboring gene NIMA-related kinase 2 Neighboring gene insulin receptor related receptor Neighboring gene platelet endothelial aggregation receptor 1 Neighboring gene leucine rich repeat containing 71

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables neurotrophin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables neurotrophin receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables neurotrophin receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
enables transmembrane receptor protein tyrosine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in axon IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
part_of receptor complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
high affinity nerve growth factor receptor
Names
neurotrophic tyrosine kinase, receptor, type 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030684.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    131628758..131707039
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002938989.5XP_002939035.2  high affinity nerve growth factor receptor

    UniProtKB/TrEMBL
    A0A6I8SLQ1, F6W3P4
    Related
    ENSXETP00000039136.5, ENSXETT00000039136.5
    Conserved Domains (6) summary
    cd05092
    Location:516795
    PTKc_TrkA; Catalytic domain of the Protein Tyrosine Kinase, Tropomyosin Related Kinase A
    sd00031
    Location:99122
    LRR_1; leucine-rich repeat [structural motif]
    pfam13855
    Location:97156
    LRR_8; Leucine rich repeat
    pfam16920
    Location:157200
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cd00096
    Location:296302
    Ig; Ig strand A [structural motif]
    cl11960
    Location:295390
    Ig; Immunoglobulin domain