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prkar2a protein kinase, cAMP-dependent, regulatory subunit type II alpha [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100486265, updated on 8-Mar-2024

Summary

Official Symbol
prkar2aprovided by Xenbase
Official Full Name
protein kinase, cAMP-dependent, regulatory subunit type II alphaprovided by Xenbase
Primary source
Xenbase:XB-GENE-982783
See related
Ensembl:ENSXETG00000009330
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Orthologs
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Genomic context

Location:
chromosome: 4
Exon count:
11
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 4 NC_030680.2 (136455341..136487513, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 4 NC_030680.1 (125927113..125958805, complement)

Chromosome 4 - NC_030680.2Genomic Context describing neighboring genes Neighboring gene transfer RNA phenylalanine (anticodon GAA) Neighboring gene inositol hexaphosphate kinase 2 Neighboring gene solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 Neighboring gene prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) Neighboring gene frizzled related protein 2

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cAMP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cAMP binding IEA
Inferred from Electronic Annotation
more info
 
enables cAMP-dependent protein kinase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables cAMP-dependent protein kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables protein kinase A catalytic subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in negative regulation of cAMP-dependent protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of cAMP-dependent protein kinase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of cAMP-dependent protein kinase complex IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cAMP-dependent protein kinase type II-alpha regulatory subunit
Names
protein kinase, cAMP-dependent, regulatory, type II, alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030680.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    136455341..136487513 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_002933058.5XP_002933104.1  cAMP-dependent protein kinase type II-alpha regulatory subunit

    UniProtKB/TrEMBL
    A0A6I8Q2A9
    Related
    ENSXETP00000066705.1, ENSXETT00000081425.2
    Conserved Domains (2) summary
    cd12103
    Location:343
    DD_RIIalpha_PKA; Dimerization/Docking domain of the Type II alpha Regulatory subunit of cAMP-dependent protein kinase
    cd00038
    Location:262382
    CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...