U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

duox1 dual oxidase 1 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100486194, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
duox1provided by Xenbase
Official Full Name
dual oxidase 1provided by Xenbase
Primary source
Xenbase:XB-GENE-1005876
See related
Ensembl:ENSXETG00000007754
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
lnox1; thox1; noxef1
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 3
Exon count:
33
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (95583024..95638630)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (85978620..86025786)

Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene dual oxidase maturation factor 1 Neighboring gene dual oxidase maturation factor 1 Neighboring gene Src homology 2 domain containing F Neighboring gene forkhead box B1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables NAD(P)H oxidase H2O2-forming activity IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables peroxidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within hormone biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within hydrogen peroxide catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to oxidative stress IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within thyroid hormone generation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
dual oxidase 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    95583024..95638630
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031899149.1 → XP_031755009.1  dual oxidase 1

    UniProtKB/TrEMBL
    A0A6I8PSX5, A0A6I8SLD4
    Related
    ENSXETP00000056553.4, ENSXETT00000056553.4
    Conserved Domains (5) summary
    cd06186
    Location:1231 → 1505
    NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
    PTZ00183
    Location:753 → 920
    PTZ00183; centrin; Provisional
    cd09820
    Location:34 → 592
    dual_peroxidase_like; Dual oxidase and related animal heme peroxidases
    PLN02292
    Location:1043 → 1374
    PLN02292; ferric-chelate reductase
    cd00051
    Location:815 → 876
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Miscellaneous