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pcsk6 proprotein convertase subtilisin/kexin type 6 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 100485543, updated on 8-Mar-2024

Summary

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Official Symbol
pcsk6provided by Xenbase
Official Full Name
proprotein convertase subtilisin/kexin type 6provided by Xenbase
Primary source
Xenbase:XB-GENE-979058
See related
Ensembl:ENSXETG00000006663
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Also known as
spc4; pace4; Xpace4
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 3
Exon count:
23
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 3 NC_030679.2 (115921184..116156263, complement)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) 3 NC_030679.1 (105877331..105954583, complement)

Chromosome 3 - NC_030679.2Genomic Context describing neighboring genes Neighboring gene selenoprotein S Neighboring gene small nuclear ribonucleoprotein polypeptide A' Neighboring gene uncharacterized LOC116409781 Neighboring gene pleckstrin homology domain containing O2 Neighboring gene ankyrin repeat and death domain containing 1A Neighboring gene SPG21, maspardin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables peptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
enables serine-type peptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within proteolysis IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
proprotein convertase subtilisin/kexin type 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030679.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    115921184..116156263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031899241.1 → XP_031755101.1  proprotein convertase subtilisin/kexin type 6 isoform X3

    UniProtKB/TrEMBL
    A0A6I8QC07, A0A8J1JEN7
    Related
    ENSXETP00000066042.2, ENSXETT00000097572.2
    Conserved Domains (6) summary
    cd04059
    Location:30 → 324
    Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
    smart00261
    Location:707 → 749
    FU; Furin-like repeats
    pfam01483
    Location:415 → 505
    P_proprotein; Proprotein convertase P-domain
    pfam08686
    Location:805 → 828
    PLAC; PLAC (protease and lacunin) domain
    pfam14843
    Location:557 → 676
    GF_recep_IV; Growth factor receptor domain IV
    pfam16470
    Location:1 → 19
    S8_pro-domain; Peptidase S8 pro-domain

  2. XM_018092475.2 → XP_017947964.1  proprotein convertase subtilisin/kexin type 6 isoform X1

    UniProtKB/TrEMBL
    A0A6I8SRI2, A0A8J0SZJ1
    Conserved Domains (7) summary
    cd04059
    Location:115 → 409
    Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
    smart00261
    Location:792 → 834
    FU; Furin-like repeats
    pfam01483
    Location:500 → 590
    P_proprotein; Proprotein convertase P-domain
    pfam08686
    Location:890 → 913
    PLAC; PLAC (protease and lacunin) domain
    pfam14843
    Location:642 → 761
    GF_recep_IV; Growth factor receptor domain IV
    pfam15913
    Location:798 → 880
    Furin-like_2; Furin-like repeat, cysteine-rich
    pfam16470
    Location:28 → 104
    S8_pro-domain; Peptidase S8 pro-domain

  3. XM_002939262.5 → XP_002939308.2  proprotein convertase subtilisin/kexin type 6 isoform X2

    UniProtKB/TrEMBL
    A0A6I8QTT2, A0A6I8SRI2
    Related
    ENSXETP00000072594.2, ENSXETT00000085639.2
    Conserved Domains (7) summary
    cd04059
    Location:115 → 409
    Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
    smart00261
    Location:786 → 828
    FU; Furin-like repeats
    pfam01483
    Location:494 → 584
    P_proprotein; Proprotein convertase P-domain
    pfam08686
    Location:884 → 907
    PLAC; PLAC (protease and lacunin) domain
    pfam14843
    Location:636 → 755
    GF_recep_IV; Growth factor receptor domain IV
    pfam15913
    Location:792 → 874
    Furin-like_2; Furin-like repeat, cysteine-rich
    pfam16470
    Location:28 → 104
    S8_pro-domain; Peptidase S8 pro-domain
Nucleotide Protein Strain
Heading Accession and Version

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