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ARHGAP24 Rho GTPase activating protein 24 [ Ailuropoda melanoleuca (giant panda) ]

Gene ID: 100478203, updated on 8-Mar-2024

Summary

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Gene symbol
ARHGAP24
Gene description
Rho GTPase activating protein 24
Locus tag
PANDA_001463
See related
Ensembl:ENSAMEG00000003558
Gene type
protein coding
RefSeq status
MODEL
Organism
Ailuropoda melanoleuca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ailuropoda
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
14
Annotation release Status Assembly Chr Location
103 current ASM200744v2 (GCF_002007445.1) 11 NC_048228.1 (42105008..42605485, complement)
102 previous assembly AilMel_1.0 (GCF_000004335.2) Unplaced Scaffold NW_003217314.1 (2480333..2969536, complement)

Chromosome 11 - NC_048228.1Genomic Context describing neighboring genes Neighboring gene ATP synthase F(0) complex subunit C2, mitochondrial-like Neighboring gene U6 spliceosomal RNA Neighboring gene mitogen-activated protein kinase 10 Neighboring gene uncharacterized LOC117804410 Neighboring gene uncharacterized LOC109490603 Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1-like Neighboring gene 40S ribosomal protein S15a-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of Rac protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of ruffle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in wound healing, spreading of epidermal cells IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 24

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ailuropoda melanoleuca Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM200744v2 Primary Assembly

Genomic

  1. NC_048228.1 Reference ASM200744v2 Primary Assembly

    Range
    42105008..42605485 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_034671582.1 → XP_034527473.1  rho GTPase-activating protein 24 isoform X1

    UniProtKB/TrEMBL
    A0A7N5JKH5

  2. XM_002913592.4 → XP_002913638.1  rho GTPase-activating protein 24 isoform X2

    UniProtKB/TrEMBL
    A0A7N5JKH5
    Related
    ENSAMEP00000026702.1, ENSAMET00000036238.1
    Conserved Domains (4) summary
    cd04390
    Location:131 → 329
    RhoGAP_ARHGAP22_24_25; RhoGAP_ARHGAP22_24_25: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been ...
    cd13379
    Location:19 → 131
    PH_RhoGap24; Rho GTPase activating protein 24 Pleckstrin homology (PH) domain
    pfam00169
    Location:21 → 124
    PH; PH domain
    pfam15035
    Location:662 → 739
    Rootletin; Ciliary rootlet component, centrosome cohesion

  3. XM_019806282.2 → XP_019661841.1  rho GTPase-activating protein 24 isoform X3

    UniProtKB/TrEMBL
    D2GX70
    Related
    ENSAMEP00000003759.2, ENSAMET00000003910.2

  4. XM_034671584.1 → XP_034527475.1  rho GTPase-activating protein 24 isoform X3

    UniProtKB/TrEMBL
    D2GX70

  5. XM_002913594.4 → XP_002913640.2  rho GTPase-activating protein 24 isoform X4

    UniProtKB/TrEMBL
    A0A7N5KKX6
    Related
    ENSAMEP00000041687.1, ENSAMET00000029091.1
    Conserved Domains (2) summary
    cd04390
    Location:39 → 237
    RhoGAP_ARHGAP22_24_25; RhoGAP_ARHGAP22_24_25: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP22, 24 and 25-like proteins; longer isoforms of these proteins contain an additional N-terminal pleckstrin homology (PH) domain. ARHGAP25 (KIA0053) has been ...
    pfam15035
    Location:570 → 647
    Rootletin; Ciliary rootlet component, centrosome cohesion
Nucleotide Protein
Heading Accession and Version

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