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MYCBP2 MYC binding protein 2 [ Pongo abelii (Sumatran orangutan) ]

Gene ID: 100451266, updated on 3-Apr-2024

Summary

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Gene symbol
MYCBP2
Gene description
MYC binding protein 2
Locus tag
CR201_G0007538
See related
Ensembl:ENSPPYG00000029658
Gene type
protein coding
RefSeq status
MODEL
Organism
Pongo abelii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
87
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2) 14 NC_071999.2 (82781100..83057865, complement)
RS_2023_04 previous assembly NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1) 13 NC_071998.1 (65565158..65840946, complement)

Chromosome 14 - NC_071999.2Genomic Context describing neighboring genes Neighboring gene CLN5 intracellular trafficking protein Neighboring gene F-box and leucine rich repeat protein 3 Neighboring gene U2 spliceosomal RNA Neighboring gene uncharacterized LOC129049565 Neighboring gene uncharacterized LOC129049689

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of synaptic assembly at neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase MYCBP2
Names
MYC binding protein 2, E3 ubiquitin protein ligase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_028885655.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

Genomic

  1. NC_071999.2 Reference NHGRI_mPonAbe1-v2.0_pri Primary Assembly

    Range
    82781100..83057865 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054529141.2 → XP_054385116.1  E3 ubiquitin-protein ligase MYCBP2 isoform X7

  2. XM_024230800.3 → XP_024086568.1  E3 ubiquitin-protein ligase MYCBP2 isoform X19

    UniProtKB/TrEMBL
    A0A2J8WU53
    Conserved Domains (9) summary
    pfam00415
    Location:958 → 1006
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:1727 → 1882
    PHR; PHR domain
    pfam11702
    Location:2805 → 2948
    DUF3295; Protein of unknown function (DUF3295)
    pfam13540
    Location:943 → 971
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cd16463
    Location:4350 → 4404
    RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
    cl02148
    Location:3673 → 3765
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    cl25836
    Location:2650 → 2855
    Retinal; Retinal protein
    cl27659
    Location:2394 → 2445
    Filamin; Filamin/ABP280 repeat
    cl27697
    Location:527 → 716
    RCC1; Regulator of chromosome condensation (RCC1) repeat

  3. XM_024230799.3 → XP_024086567.1  E3 ubiquitin-protein ligase MYCBP2 isoform X18

    UniProtKB/TrEMBL
    A0A2J8WU53
    Conserved Domains (9) summary
    pfam00415
    Location:958 → 1006
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:1727 → 1882
    PHR; PHR domain
    pfam12004
    Location:2601 → 2855
    DUF3498; Domain of unknown function (DUF3498)
    pfam13540
    Location:943 → 971
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cd16463
    Location:4402 → 4456
    RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
    cl02148
    Location:3725 → 3817
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    cl27659
    Location:2394 → 2445
    Filamin; Filamin/ABP280 repeat
    cl27697
    Location:527 → 716
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    cl28034
    Location:2776 → 2984
    Herpes_ICP4_N; Herpesvirus ICP4-like protein N-terminal region

  4. XM_054529145.2 → XP_054385120.1  E3 ubiquitin-protein ligase MYCBP2 isoform X15

  5. XM_024230798.3 → XP_024086566.1  E3 ubiquitin-protein ligase MYCBP2 isoform X17

    UniProtKB/TrEMBL
    A0A2J8WU53
    Conserved Domains (9) summary
    pfam00415
    Location:958 → 1006
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:1727 → 1882
    PHR; PHR domain
    pfam11702
    Location:2861 → 3004
    DUF3295; Protein of unknown function (DUF3295)
    pfam13540
    Location:943 → 971
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cd16463
    Location:4406 → 4460
    RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
    cl02148
    Location:3729 → 3821
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    cl25836
    Location:2706 → 2911
    Retinal; Retinal protein
    cl27659
    Location:2394 → 2445
    Filamin; Filamin/ABP280 repeat
    cl27697
    Location:527 → 716
    RCC1; Regulator of chromosome condensation (RCC1) repeat

  6. XM_063714988.1 → XP_063571058.1  E3 ubiquitin-protein ligase MYCBP2 isoform X13

  7. XM_054529142.2 → XP_054385117.1  E3 ubiquitin-protein ligase MYCBP2 isoform X9

  8. XM_024230796.3 → XP_024086564.1  E3 ubiquitin-protein ligase MYCBP2 isoform X16

    UniProtKB/TrEMBL
    A0A2J8WU53, K7EUD0
    Related
    ENSPPYP00000024154.2
    Conserved Domains (9) summary
    pfam00415
    Location:958 → 1006
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:1727 → 1882
    PHR; PHR domain
    pfam11702
    Location:2880 → 3023
    DUF3295; Protein of unknown function (DUF3295)
    pfam13540
    Location:943 → 971
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cd16463
    Location:4425 → 4479
    RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
    cl02148
    Location:3748 → 3840
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    cl25836
    Location:2725 → 2930
    Retinal; Retinal protein
    cl27659
    Location:2394 → 2445
    Filamin; Filamin/ABP280 repeat
    cl27697
    Location:527 → 716
    RCC1; Regulator of chromosome condensation (RCC1) repeat

  9. XM_054529144.2 → XP_054385119.1  E3 ubiquitin-protein ligase MYCBP2 isoform X12

  10. XM_054529140.2 → XP_054385115.1  E3 ubiquitin-protein ligase MYCBP2 isoform X5

  11. XM_063714987.1 → XP_063571057.1  E3 ubiquitin-protein ligase MYCBP2 isoform X10

  12. XM_054529139.2 → XP_054385114.1  E3 ubiquitin-protein ligase MYCBP2 isoform X4

  13. XM_024230795.3 → XP_024086563.1  E3 ubiquitin-protein ligase MYCBP2 isoform X14

    UniProtKB/TrEMBL
    A0A2J8WU53
    Conserved Domains (9) summary
    pfam00415
    Location:958 → 1006
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:1727 → 1882
    PHR; PHR domain
    pfam11702
    Location:2905 → 3048
    DUF3295; Protein of unknown function (DUF3295)
    pfam13540
    Location:943 → 971
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cd16463
    Location:4450 → 4504
    RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
    cl02148
    Location:3773 → 3865
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    cl25836
    Location:2750 → 2955
    Retinal; Retinal protein
    cl27659
    Location:2394 → 2445
    Filamin; Filamin/ABP280 repeat
    cl27697
    Location:527 → 716
    RCC1; Regulator of chromosome condensation (RCC1) repeat

  14. XM_054529143.2 → XP_054385118.1  E3 ubiquitin-protein ligase MYCBP2 isoform X11

  15. XM_024230801.3 → XP_024086569.1  E3 ubiquitin-protein ligase MYCBP2 isoform X21

    UniProtKB/TrEMBL
    A0A2J8WU53
    Conserved Domains (9) summary
    pfam00415
    Location:958 → 1006
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:1727 → 1882
    PHR; PHR domain
    pfam12004
    Location:2701 → 2955
    DUF3498; Domain of unknown function (DUF3498)
    pfam13540
    Location:943 → 971
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cd16463
    Location:4499 → 4553
    RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
    cl02148
    Location:3825 → 3917
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    cl27659
    Location:2394 → 2445
    Filamin; Filamin/ABP280 repeat
    cl27697
    Location:527 → 716
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    cl28034
    Location:2876 → 3084
    Herpes_ICP4_N; Herpesvirus ICP4-like protein N-terminal region

  16. XM_024230791.3 → XP_024086559.1  E3 ubiquitin-protein ligase MYCBP2 isoform X8

    UniProtKB/TrEMBL
    A0A2J8WU53
    Conserved Domains (9) summary
    pfam00415
    Location:958 → 1006
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:1727 → 1882
    PHR; PHR domain
    pfam12004
    Location:2701 → 2955
    DUF3498; Domain of unknown function (DUF3498)
    pfam13540
    Location:943 → 971
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cd16463
    Location:4502 → 4556
    RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
    cl02148
    Location:3825 → 3917
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    cl27659
    Location:2394 → 2445
    Filamin; Filamin/ABP280 repeat
    cl27697
    Location:527 → 716
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    cl28034
    Location:2876 → 3084
    Herpes_ICP4_N; Herpesvirus ICP4-like protein N-terminal region

  17. XM_054529137.2 → XP_054385112.1  E3 ubiquitin-protein ligase MYCBP2 isoform X3

  18. XM_024230789.3 → XP_024086557.1  E3 ubiquitin-protein ligase MYCBP2 isoform X6

    UniProtKB/TrEMBL
    A0A2J8WU53
    Conserved Domains (9) summary
    pfam00415
    Location:958 → 1006
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam08005
    Location:1727 → 1882
    PHR; PHR domain
    pfam11702
    Location:2965 → 3108
    DUF3295; Protein of unknown function (DUF3295)
    pfam13540
    Location:943 → 971
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat
    cd16463
    Location:4510 → 4564
    RING-H2_PHR; RING finger, H2 subclass, found in the PHR protein family
    cl02148
    Location:3833 → 3925
    APC10-like; APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination
    cl25836
    Location:2810 → 3015
    Retinal; Retinal protein
    cl27659
    Location:2394 → 2445
    Filamin; Filamin/ABP280 repeat
    cl27697
    Location:527 → 716
    RCC1; Regulator of chromosome condensation (RCC1) repeat

  19. XM_054529136.2 → XP_054385111.1  E3 ubiquitin-protein ligase MYCBP2 isoform X2

  20. XM_054529135.2 → XP_054385110.1  E3 ubiquitin-protein ligase MYCBP2 isoform X1

  21. XM_054529146.2 → XP_054385121.1  E3 ubiquitin-protein ligase MYCBP2 isoform X20

Nucleotide Protein
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