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ECT2 epithelial cell transforming 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100356055, updated on 8-Mar-2024

Summary

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Gene symbol
ECT2
Gene description
epithelial cell transforming 2
See related
Ensembl:ENSOCUG00000009484
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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See ECT2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 14 NC_067387.1 (68843133..68914744)

Chromosome 14 - NC_067387.1Genomic Context describing neighboring genes Neighboring gene TNF superfamily member 10 Neighboring gene neutral cholesterol ester hydrolase 1 Neighboring gene 40S ribosomal protein S26-like Neighboring gene ganglioside GM2 activator-like Neighboring gene heat shock cognate 71 kDa protein Neighboring gene spermatogenesis associated 16

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067387.1 Chromosome 14 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cytokinesis, actomyosin contractile ring assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein ECT2
Names
epithelial cell transforming sequence 2 oncogene protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067387.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    68843133..68914744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008266501.3 → XP_008264723.1  protein ECT2 isoform X1

    UniProtKB/TrEMBL
    A0A5F9C505, A0A5F9CJ77
    Related
    ENSOCUP00000033530.1
    Conserved Domains (4) summary
    cd01229
    Location:631 → 804
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:266 → 341
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:456 → 640
    RhoGEF; RhoGEF domain
    pfam12738
    Location:179 → 242
    PTCB-BRCT; twin BRCT domain

  2. XM_002716427.4 → XP_002716473.1  protein ECT2 isoform X2

    UniProtKB/TrEMBL
    A0A5F9C505, A0A5F9D5C8
    Related
    ENSOCUP00000041372.1
    Conserved Domains (4) summary
    cd01229
    Location:600 → 773
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:235 → 310
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:425 → 609
    RhoGEF; RhoGEF domain
    pfam12738
    Location:148 → 211
    PTCB-BRCT; twin BRCT domain

RNA

  1. XR_007924607.1 RNA Sequence

  2. XR_007924608.1 RNA Sequence

  3. XR_007924609.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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