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CDK12 cyclin dependent kinase 12 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100354313, updated on 3-Apr-2024

Summary

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Gene symbol
CDK12
Gene description
cyclin dependent kinase 12
See related
Ensembl:ENSOCUG00000000780
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 19 NC_067392.1 (38273573..38353411)

Chromosome 19 - NC_067392.1Genomic Context describing neighboring genes Neighboring gene F-box and leucine rich repeat protein 20 Neighboring gene mediator complex subunit 1 Neighboring gene uncharacterized LOC103351554 Neighboring gene uncharacterized LOC127484483

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067392.1 Chromosome 19 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II CTD heptapeptide repeat kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cyclin-dependent protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of cyclin/CDK positive transcription elongation factor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cyclin-dependent kinase 12
Names
Cdc2-related kinase, arginine/serine-rich

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067392.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    38273573..38353411
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008271401.3 → XP_008269623.2  cyclin-dependent kinase 12 isoform X2

  2. XM_017349184.2 → XP_017204673.1  cyclin-dependent kinase 12 isoform X4

    UniProtKB/TrEMBL
    G1SE21, G1U8D1
    Conserved Domains (2) summary
    smart00220
    Location:729 → 1022
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:721 → 1022
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  3. XM_008271403.3 → XP_008269625.1  cyclin-dependent kinase 12 isoform X4

    See identical proteins and their annotated locations for XP_008269625.1

    UniProtKB/TrEMBL
    G1SE21, G1U8D1
    Conserved Domains (2) summary
    smart00220
    Location:729 → 1022
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:721 → 1022
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  4. XM_008271402.3 → XP_008269624.1  cyclin-dependent kinase 12 isoform X4

    See identical proteins and their annotated locations for XP_008269624.1

    UniProtKB/TrEMBL
    G1SE21, G1U8D1
    Related
    ENSOCUP00000025696.2
    Conserved Domains (2) summary
    smart00220
    Location:729 → 1022
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:721 → 1022
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  5. XM_051824895.1 → XP_051680855.1  cyclin-dependent kinase 12 isoform X4

    UniProtKB/TrEMBL
    G1U8D1

  6. XM_051824894.1 → XP_051680854.1  cyclin-dependent kinase 12 isoform X4

    UniProtKB/TrEMBL
    G1U8D1

  7. XM_051824896.1 → XP_051680856.1  cyclin-dependent kinase 12 isoform X4

    UniProtKB/TrEMBL
    G1U8D1

  8. XM_002719339.4 → XP_002719385.2  cyclin-dependent kinase 12 isoform X1

  9. XM_002719338.4 → XP_002719384.2  cyclin-dependent kinase 12 isoform X3

  10. XM_017349185.2 → XP_017204674.1  cyclin-dependent kinase 12 isoform X6

    UniProtKB/TrEMBL
    G1SE21
    Conserved Domains (2) summary
    smart00220
    Location:729 → 1022
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:721 → 1022
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  11. XM_008271408.3 → XP_008269630.1  cyclin-dependent kinase 12 isoform X6

    See identical proteins and their annotated locations for XP_008269630.1

    UniProtKB/TrEMBL
    G1SE21
    Conserved Domains (2) summary
    smart00220
    Location:729 → 1022
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:721 → 1022
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  12. XM_008271407.3 → XP_008269629.1  cyclin-dependent kinase 12 isoform X6

    See identical proteins and their annotated locations for XP_008269629.1

    UniProtKB/TrEMBL
    G1SE21
    Conserved Domains (2) summary
    smart00220
    Location:729 → 1022
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd07864
    Location:721 → 1022
    STKc_CDK12; Catalytic domain of the Serine/Threonine Kinase, Cyclin-Dependent protein Kinase 12

  13. XM_051824898.1 → XP_051680858.1  cyclin-dependent kinase 12 isoform X6

  14. XM_051824897.1 → XP_051680857.1  cyclin-dependent kinase 12 isoform X5

Nucleotide Protein
Heading Accession and Version

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