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LARGE2 LARGE xylosyl- and glucuronyltransferase 2 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100349053, updated on 3-Apr-2024

Summary

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Gene symbol
LARGE2
Gene description
LARGE xylosyl- and glucuronyltransferase 2
See related
Ensembl:ENSOCUG00000001671
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Also known as
GYLTL1B
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 1 NC_067374.1 (199022550..199029000)

Chromosome 1 - NC_067374.1Genomic Context describing neighboring genes Neighboring gene Frey regulator of sperm-oocyte fusion 1 Neighboring gene peroxisomal biogenesis factor 16 Neighboring gene PHD finger protein 21A Neighboring gene cAMP responsive element binding protein 3 like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_067374.1 Chromosome 1 Reference UM_NZW_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables xylosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
xylosyl- and glucuronyltransferase LARGE2
Names
glycosyltransferase-like 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067374.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    199022550..199029000
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008270235.3 → XP_008268457.1  xylosyl- and glucuronyltransferase LARGE2 isoform X1

    See identical proteins and their annotated locations for XP_008268457.1

    UniProtKB/TrEMBL
    A0A5F9DKZ0
    Related
    ENSOCUP00000046258.1
    Conserved Domains (3) summary
    cd06431
    Location:99 → 378
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    COG1442
    Location:100 → 347
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]
    pfam13896
    Location:433 → 666
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  2. XM_002709074.4 → XP_002709120.1  xylosyl- and glucuronyltransferase LARGE2 isoform X1

    See identical proteins and their annotated locations for XP_002709120.1

    UniProtKB/TrEMBL
    A0A5F9DKZ0
    Conserved Domains (3) summary
    cd06431
    Location:99 → 378
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    COG1442
    Location:100 → 347
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]
    pfam13896
    Location:433 → 666
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  3. XM_008270253.3 → XP_008268475.1  xylosyl- and glucuronyltransferase LARGE2 isoform X4

    UniProtKB/TrEMBL
    G1SFV9
    Conserved Domains (2) summary
    pfam13896
    Location:372 → 605
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
    cl11394
    Location:73 → 317
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  4. XM_051852699.1 → XP_051708659.1  xylosyl- and glucuronyltransferase LARGE2 isoform X3

  5. XM_008270241.3 → XP_008268463.1  xylosyl- and glucuronyltransferase LARGE2 isoform X2

    UniProtKB/TrEMBL
    G1SFV9
    Related
    ENSOCUP00000001431.4
    Conserved Domains (3) summary
    cd06431
    Location:73 → 352
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    COG1442
    Location:74 → 321
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]
    pfam13896
    Location:407 → 640
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
Nucleotide Protein
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