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PARP8 poly(ADP-ribose) polymerase family member 8 [ Oryctolagus cuniculus (rabbit) ]

Gene ID: 100343313, updated on 3-Apr-2024

Summary

Gene symbol
PARP8
Gene description
poly(ADP-ribose) polymerase family member 8
See related
Ensembl:ENSOCUG00000014454
Gene type
protein coding
RefSeq status
MODEL
Organism
Oryctolagus cuniculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
Orthologs
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Genomic context

See PARP8 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2023_02 current UM_NZW_1.0 (GCF_009806435.1) 11 NC_067384.1 (22610291..22798027, complement)

Chromosome 11 - NC_067384.1Genomic Context describing neighboring genes Neighboring gene developmental pluripotency-associated protein 2 Neighboring gene tubulin alpha-1C chain-like Neighboring gene peroxiredoxin-1-like Neighboring gene embigin

Genomic regions, transcripts, and products

Genomic Sequence:
NC_067384.1 Chromosome 11 Reference UM_NZW_1.0 Primary Assembly

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ ADP-ribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables kinase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein serine/threonine kinase activator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum tubular network IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in intracellular anatomical structure IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
protein mono-ADP-ribosyltransferase PARP8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_009806435.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UM_NZW_1.0 Primary Assembly

Genomic

  1. NC_067384.1 Reference UM_NZW_1.0 Primary Assembly

    Range
    22610291..22798027 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_051853484.1XP_051709444.1  protein mono-ADP-ribosyltransferase PARP8 isoform X2

  2. XM_051853483.1XP_051709443.1  protein mono-ADP-ribosyltransferase PARP8 isoform X1

  3. XM_051853486.1XP_051709446.1  protein mono-ADP-ribosyltransferase PARP8 isoform X4

    UniProtKB/TrEMBL
    A0A5F9C6P0
  4. XM_008262187.3XP_008260409.1  protein mono-ADP-ribosyltransferase PARP8 isoform X3

    UniProtKB/TrEMBL
    A0A5F9CYM3, G1T7F9
    Related
    ENSOCUP00000012431.2
    Conserved Domains (1) summary
    cd01341
    Location:732856
    ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...
  5. XM_051853487.1XP_051709447.1  protein mono-ADP-ribosyltransferase PARP8 isoform X5

    UniProtKB/TrEMBL
    A0A5F9DBA9