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MIOS meiosis regulator for oocyte development [ Sus scrofa (pig) ]

Gene ID: 100337662, updated on 8-Mar-2024

Summary

Official Symbol
MIOSprovided by VGNC
Official Full Name
meiosis regulator for oocyte developmentprovided by VGNC
Primary source
VGNC:VGNC:90234
See related
Ensembl:ENSSSCG00000015343
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in ovary (RPKM 6.8), spleen (RPKM 5.3) and 8 other tissues See more
Orthologs
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Genomic context

Location:
chromosome: 9
Exon count:
13
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 9 NC_010451.4 (77851764..77892417)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 9 NC_010451.3 (85517036..85547841)

Chromosome 9 - NC_010451.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106504962 Neighboring gene uncharacterized LOC110255476 Neighboring gene collagen type XXVIII alpha 1 chain Neighboring gene UBAP1-MVB12-associated (UMA) domain containing 1 Neighboring gene replication protein A3 Neighboring gene uncharacterized LOC110262233

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to amino acid starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
GATOR2 complex protein MIOS; WD repeat-containing protein mio
Names
missing oocyte, meiosis regulator-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195353.1NP_001182282.1  GATOR2 complex protein MIOS

    See identical proteins and their annotated locations for NP_001182282.1

    Status: PROVISIONAL

    Source sequence(s)
    GU373700
    UniProtKB/TrEMBL
    A0A4X1TNS1, A0A8D0WIX2, A0A8D1D608, D3K5M2, I3LJ97
    Conserved Domains (3) summary
    COG2319
    Location:97368
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:64105
    7WD40; WD40 repeat [structural motif]
    cd16691
    Location:782858
    mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010451.4 Reference Sscrofa11.1 Primary Assembly

    Range
    77851764..77892417
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021101997.1XP_020957656.1  WD repeat-containing protein mio isoform X3

    UniProtKB/TrEMBL
    A0A4X1TRD0, A0A8D1C6H4, A0A8D1D608
    Conserved Domains (3) summary
    COG2319
    Location:97368
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:64105
    7WD40; WD40 repeat [structural motif]
    cd16691
    Location:729805
    mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins
  2. XM_021101993.1XP_020957652.1  WD repeat-containing protein mio isoform X1

    UniProtKB/TrEMBL
    A0A4X1TNS1, A0A8D0WIX2, A0A8D1D608, D3K5M2, I3LJ97
    Related
    ENSSSCP00000057657.1, ENSSSCT00000047612.3
    Conserved Domains (3) summary
    COG2319
    Location:97368
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:64105
    7WD40; WD40 repeat [structural motif]
    cd16691
    Location:782858
    mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins
  3. XM_021101994.1XP_020957653.1  WD repeat-containing protein mio isoform X1

    UniProtKB/TrEMBL
    A0A4X1TNS1, A0A8D0WIX2, A0A8D1D608, D3K5M2, I3LJ97
    Conserved Domains (3) summary
    COG2319
    Location:97368
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:64105
    7WD40; WD40 repeat [structural motif]
    cd16691
    Location:782858
    mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins
  4. XM_021101996.1XP_020957655.1  WD repeat-containing protein mio isoform X2

    UniProtKB/TrEMBL
    A0A286ZUW7, A0A4X1TRL9, A0A8D0J2Q5, A0A8D0J4G8, A0A8D0MRN2
    Conserved Domains (3) summary
    sd00039
    Location:64105
    7WD40; WD40 repeat [structural motif]
    cl24077
    Location:737794
    Zn_ribbon_17; Zinc-ribbon, C4HC2 type
    cl25539
    Location:84297
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  5. XM_021101998.1XP_020957657.1  WD repeat-containing protein mio isoform X3

    UniProtKB/TrEMBL
    A0A4X1TRD0, A0A8D1C6H4, A0A8D1D608
    Conserved Domains (3) summary
    COG2319
    Location:97368
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:64105
    7WD40; WD40 repeat [structural motif]
    cd16691
    Location:729805
    mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins
  6. XM_021101995.1XP_020957654.1  WD repeat-containing protein mio isoform X2

    UniProtKB/TrEMBL
    A0A286ZUW7, A0A4X1TRL9, A0A8D0J2Q5, A0A8D0J4G8, A0A8D0MRN2
    Related
    ENSSSCP00000035285.2, ENSSSCT00000037144.3
    Conserved Domains (3) summary
    sd00039
    Location:64105
    7WD40; WD40 repeat [structural motif]
    cl24077
    Location:737794
    Zn_ribbon_17; Zinc-ribbon, C4HC2 type
    cl25539
    Location:84297
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...