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DGKE diacylglycerol kinase epsilon [ Sus scrofa (pig) ]

Gene ID: 100312967, updated on 8-Mar-2024

Summary

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Official Symbol
DGKEprovided by VGNC
Official Full Name
diacylglycerol kinase epsilonprovided by VGNC
Primary source
VGNC:VGNC:87271
See related
Ensembl:ENSSSCG00000017615
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in lung (RPKM 3.6), spleen (RPKM 3.3) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
12
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (33141439..33172412)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (34090097..34122581)

Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene noggin Neighboring gene chromosome 12 C17orf67 homolog Neighboring gene uncharacterized LOC110256032 Neighboring gene tripartite motif containing 25

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein kinase C-activating G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase epsilon
Names
diacylglycerol kinase, epsilon 64kDa
NP_001161117.1
XP_005657020.2
XP_013845395.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167645.1 → NP_001161117.1  diacylglycerol kinase epsilon

    See identical proteins and their annotated locations for NP_001161117.1

    Status: PROVISIONAL

    Source sequence(s)
    AB529455
    UniProtKB/TrEMBL
    A0A4X1SG45, A0A8D0K2K9, D0G6S2
    Related
    ENSSSCP00000070556.1, ENSSSCT00000085677.2
    Conserved Domains (4) summary
    smart00046
    Location:218 → 346
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:122 → 166
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl00040
    Location:57 → 106
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl02440
    Location:366 → 426
    DAGK_acc; Diacylglycerol kinase accessory domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

    Range
    33141439..33172412
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005656963.3 → XP_005657020.2  diacylglycerol kinase epsilon isoform X1

    UniProtKB/TrEMBL
    A0A4X1SGI9, A0A8D0JUR9, A0A8D0NLU7
    Related
    ENSSSCP00000046820.2, ENSSSCT00000044738.3
    Conserved Domains (4) summary
    smart00045
    Location:366 → 521
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:218 → 346
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:122 → 166
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl00040
    Location:57 → 106
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...

  2. XM_013989941.2 → XP_013845395.2  diacylglycerol kinase epsilon isoform X1

    UniProtKB/TrEMBL
    A0A4X1SGI9, A0A8D0JUR9, A0A8D0NLU7
    Related
    ENSSSCP00000032152.2, ENSSSCT00000043690.2
    Conserved Domains (4) summary
    smart00045
    Location:366 → 521
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:218 → 346
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00029
    Location:122 → 166
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cl00040
    Location:57 → 106
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
Nucleotide Protein
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