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DEFB1 beta-defensin 1 [ Bos taurus (cattle) ]

Gene ID: 100297617, updated on 8-Feb-2024

Summary

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Gene symbol
DEFB1
Gene description
beta-defensin 1
See related
Ensembl:ENSBTAG00000053456
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Bos taurus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Also known as
BNBD-1
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Genomic context

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Location:
chromosome: 27
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_09 current ARS-UCD2.0 (GCF_002263795.3) 27 NC_037354.1 (6721772..6723692)

Chromosome 27 - NC_037354.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC132344039 Neighboring gene defensin beta 7 Neighboring gene beta-defensin 33-like Neighboring gene uncharacterized LOC112444643

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_037354.1 Chromosome 27 Reference ARS-UCD2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils. Selsted ME, et al. J Biol Chem, 1993 Mar 25. PMID 8454635
  2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CCR6 chemokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chemoattractant activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-defensin 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001324544.1 → NP_001311473.1  beta-defensin 1 precursor

    Status: PROVISIONAL

    Source sequence(s)
    EV653719
    UniProtKB/TrEMBL
    A0A3Q1LKP4
    Related
    ENSBTAP00000062422.2, ENSBTAT00000069740.2

RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2023_09

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UCD2.0 Primary Assembly

Genomic

  1. NC_037354.1 Reference ARS-UCD2.0 Primary Assembly

    Range
    6721772..6723692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P46159.1 GenPept UniProtKB/Swiss-Prot:P46159

Gene LinkOut

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