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socs1.L suppressor of cytokine signaling 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 100294520, updated on 11-Apr-2024

Summary

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Official Symbol
socs1.L
Official Full Name
suppressor of cytokine signaling 1 L homeolog
Primary source
Xenbase:XB-GENE-6372205
Locus tag
XELAEV_18045139mg
See related
EnsemblRapid:ENSXLAG00005026262
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
jab; cis1; ssi1; tip3; cish1; ssi-1; socs-1; socs1b; socs1-a; socs1-b
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Genomic context

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Location:
chromosome: 9_10L
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (99437587..99441690, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (88855610..88859712, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene dexamethasone-induced protein Neighboring gene C-type lectin domain family 16 member A L homeolog Neighboring gene uncharacterized LOC108701886 Neighboring gene RecQ mediated genome instability 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within negative regulation of signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein ubiquitination IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
suppressor of cytokine signaling 1 L homeolog
Names
suppressor of cytokine signaling 1b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159688.1 → NP_001153160.1  suppressor of cytokine signaling 1 L homeolog

    See identical proteins and their annotated locations for NP_001153160.1

    Status: PROVISIONAL

    Source sequence(s)
    FJ696649
    UniProtKB/TrEMBL
    A0A974H400, C0LEJ4
    Conserved Domains (2) summary
    cd10382
    Location:68 → 165
    SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03735
    Location:169 → 211
    SOCS_SOCS1; SOCS (suppressors of cytokine signaling) box of SOCS1-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS1, like CIS1 and SOCS3, is involved in the ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    99437587..99441690 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018233954.2 → XP_018089443.1  suppressor of cytokine signaling 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H400, C0LEJ4
    Conserved Domains (2) summary
    cd10382
    Location:68 → 165
    SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03735
    Location:169 → 211
    SOCS_SOCS1; SOCS (suppressors of cytokine signaling) box of SOCS1-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS1, like CIS1 and SOCS3, is involved in the ...

  2. XM_041575446.1 → XP_041431380.1  suppressor of cytokine signaling 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H400, C0LEJ4
    Related
    ENSXLAP00005078010.1, ENSXLAT00005079601.1
    Conserved Domains (2) summary
    cd10382
    Location:68 → 165
    SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03735
    Location:169 → 211
    SOCS_SOCS1; SOCS (suppressors of cytokine signaling) box of SOCS1-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS1, like CIS1 and SOCS3, is involved in the ...

  3. XM_018233955.2 → XP_018089444.1  suppressor of cytokine signaling 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H400, C0LEJ4
    Conserved Domains (2) summary
    cd10382
    Location:68 → 165
    SH2_SOCS1; Src homology 2 (SH2) domain found in suppressor of cytokine signaling (SOCS) proteins
    cd03735
    Location:169 → 211
    SOCS_SOCS1; SOCS (suppressors of cytokine signaling) box of SOCS1-like proteins. Together with CIS1, the CIS/SOCS family of proteins is characterized by the presence of a C-terminal SOCS box and a central SH2 domain. SOCS1, like CIS1 and SOCS3, is involved in the ...
Nucleotide Protein Strain
Heading Accession and Version

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