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HCK HCK proto-oncogene, Src family tyrosine kinase [ Taeniopygia guttata (zebra finch) ]

Gene ID: 100220059, updated on 11-Apr-2024

Summary

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Gene symbol
HCK
Gene description
HCK proto-oncogene, Src family tyrosine kinase
See related
Ensembl:ENSTGUG00000006558
Gene type
protein coding
RefSeq status
MODEL
Organism
Taeniopygia guttata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae; Estrildinae; Taeniopygia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bTaeGut1.4.pri (GCF_003957565.2) 20 NC_044232.2 (7491831..7501320, complement)
105 previous assembly bTaeGut2.pat.W.v2 (GCF_008822105.2) 20 NC_045018.1 (7744513..7753929, complement)

Chromosome 20 - NC_044232.2Genomic Context describing neighboring genes Neighboring gene PLAG1 like zinc finger 2 Neighboring gene transmembrane 9 superfamily member 4 Neighboring gene CCM2 like scaffold protein Neighboring gene XK related 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase HCK
Names
hemopoietic cell kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Taeniopygia guttata Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bTaeGut1.4.pri Primary Assembly

Genomic

  1. NC_044232.2 Reference bTaeGut1.4.pri Primary Assembly

    Range
    7491831..7501320 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041720271.1 → XP_041576205.1  tyrosine-protein kinase HCK

    UniProtKB/TrEMBL
    H0Z868
    Conserved Domains (3) summary
    cl15255
    Location:121 → 222
    SH2; Src homology 2 (SH2) domain
    cl17036
    Location:63 → 115
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:235 → 506
    PKc_like; Protein Kinases, catalytic domain

  2. XM_030288796.3 → XP_030144656.3  tyrosine-protein kinase HCK

    UniProtKB/TrEMBL
    H0Z868
    Conserved Domains (3) summary
    cl15255
    Location:121 → 222
    SH2; Src homology 2 (SH2) domain
    cl17036
    Location:63 → 115
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:235 → 506
    PKc_like; Protein Kinases, catalytic domain

  3. XM_030288797.3 → XP_030144657.3  tyrosine-protein kinase HCK

    UniProtKB/TrEMBL
    H0Z868
    Conserved Domains (3) summary
    cl15255
    Location:121 → 222
    SH2; Src homology 2 (SH2) domain
    cl17036
    Location:63 → 115
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:235 → 506
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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