pck1 phosphoenolpyruvate carboxykinase 1 (soluble) [Salmo salar (Atlantic salmon)] - Gene

Summary

Gene symbol: pck1
Gene description: phosphoenolpyruvate carboxykinase 1 (soluble)
See related: Ensembl:ENSSSAG00000076245
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Salmo salar
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Salmo
Also known as: ppckc
Orthologs: human zebrafish all
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Genomic context

Location:: chromosome: ssa12

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
102	current	Ssal_v3.1 (GCF_905237065.1)	ssa12	NC_059453.1 (43114023..43118449, complement)
100	previous assembly	ICSASG_v2 (GCF_000233375.1)	ssa12	NC_027311.1 (35572221..35576647, complement)

Chromosome ssa12 - NC_059453.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables manganese ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables phosphoenolpyruvate carboxykinase (GTP) activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cellular response to dexamethasone stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to glucose stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to insulin stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in gluconeogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glycerol biosynthetic process from pyruvate	IEA Inferred from Electronic Annotation more info	PubMed
involved_in hepatocyte differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in propionate catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to starvation	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: phosphoenolpyruvate carboxykinase, cytosolic [GTP]

Names: Phosphoenolpyruvate carboxykinase, cytosolic

NP_001133921.1

EC 4.1.1.32

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001140449.1 → NP_001133921.1 phosphoenolpyruvate carboxykinase, cytosolic [GTP]

See identical proteins and their annotated locations for NP_001133921.1

Status: PROVISIONAL

Source sequence(s)

BT045880

UniProtKB/TrEMBL

B5X4B1

Related

ENSSSAP00000105186.1, ENSSSAT00000139881.2

Conserved Domains (1) summary

cd00819
Location:27 → 616

PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...