PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit [Pongo abelii (Sumatran orangutan)] - Gene

Summary

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Gene symbol: PRKAB1
Gene description: protein kinase, AMP-activated, beta 1 non-catalytic subunit
See related: Ensembl:ENSPPYG00000005018
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Annotation information: Annotation category: partial on reference assembly

Genomic context

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Location :: chromosome: 12

Sequence :: Chromosome: 12; NC_012603.1 (121864525..121878121)

See PRKAB1 in MapViewer

Chromosome 12 - NC_012603.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from BioSystems

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Adipocytokine signaling pathway, organism-specific biosystem (from KEGG)
Adipocytokine signaling pathway, organism-specific biosystemIncreased adipocyte volume and number are positively correlated with leptin production, and negatively correlated with production of adiponectin. Leptin is an important regulator of energy intake and...
Adipocytokine signaling pathway, conserved biosystem (from KEGG)
Adipocytokine signaling pathway, conserved biosystemIncreased adipocyte volume and number are positively correlated with leptin production, and negatively correlated with production of adiponectin. Leptin is an important regulator of energy intake and...
Circadian rhythm, organism-specific biosystem (from KEGG)
Circadian rhythm, organism-specific biosystemCircadian rhythm is an internal biological clock, which enables to sustain an approximately 24-hour rhythm in the absence of environmental cues. In mammals, the circadian clock mechanism consists of ...
Circadian rhythm, conserved biosystem (from KEGG)
Circadian rhythm, conserved biosystemCircadian rhythm is an internal biological clock, which enables to sustain an approximately 24-hour rhythm in the absence of environmental cues. In mammals, the circadian clock mechanism consists of ...
Hypertrophic cardiomyopathy (HCM), organism-specific biosystem (from KEGG)
Hypertrophic cardiomyopathy (HCM), organism-specific biosystemHypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant pattern of inheritance that is characterized by hypertrophy of the left ventricles with histological feat...
Hypertrophic cardiomyopathy (HCM), conserved biosystem (from KEGG)
Hypertrophic cardiomyopathy (HCM), conserved biosystemHypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant pattern of inheritance that is characterized by hypertrophy of the left ventricles with histological feat...
Insulin signaling pathway, organism-specific biosystem (from KEGG)
Insulin signaling pathway, organism-specific biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
Insulin signaling pathway, conserved biosystem (from KEGG)
Insulin signaling pathway, conserved biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...

General gene information

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Markers

G19710 (e-PCR)
- UniSTS:10112

A001W18 (e-PCR)
- UniSTS:10113

WI-13962 (e-PCR)
- UniSTS:25505

WI-19637 (e-PCR)
- UniSTS:4787

G44705 (e-PCR)
- UniSTS:95180

SHGC-81002 (e-PCR)
- UniSTS:102624

RH48906 (e-PCR)
- UniSTS:74209

Homology

OrthoDB: The Hierarchical Catalog of Eukaryotic Orthologs

General protein information

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Preferred Names: 5'-AMP-activated protein kinase subunit beta-1

Names: 5'-AMP-activated protein kinase subunit beta-1; AMPKb; AMPK subunit beta-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001132759.1 → NP_001126231.1 5'-AMP-activated protein kinase subunit beta-1

Status: PROVISIONAL

Source sequence(s)

CR859955

UniProtKB/Swiss-Prot

Q5R801

Related

ENSPPYP00000005719, ENSPPYT00000005939

Conserved Domains (2) summary

smart01010
Location:181 – 256
Blast Score: 282

AMPKBI; 5'-AMP-activated protein kinase beta subunit, interation domain

cd02859
Location:79 – 155
Blast Score: 304

E_set_AMPKbeta_like_N; N-terminal Early set domain, a glycogen binding domain, associated with the catalytic domain of AMP-activated protein kinase beta subunit