PAK6 p21 (RAC1) activated kinase 6 [Pongo abelii (Sumatran orangutan)] - Gene

Summary

Gene symbol: PAK6
Gene description: p21 (RAC1) activated kinase 6
See related: Ensembl:ENSPPYG00000006346
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Pongo abelii
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pongo
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	NHGRI_mPonAbe1-v2.0_pri (GCF_028885655.2)	16	NC_072001.2 (43137712..43176158)
RS_2023_04	previous assembly	NHGRI_mPonAbe1-v1.1-hic.freeze_pri (GCF_028885655.1)	15	NC_072000.1 (40417374..40455820)

Chromosome 16 - NC_072001.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-56872 (e-PCR)
- UniSTS:25943

WI-21468 (e-PCR)
- UniSTS:26519

SHGC-82160 (e-PCR)
- UniSTS:103072

RH119303 (e-PCR)
- UniSTS:133865

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in intracellular signal transduction	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protein phosphorylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of MAPK cascade	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: serine/threonine-protein kinase PAK 6

Names: BUB1B-PAK6; PAK-6; p21 protein (Cdc42/Rac)-activated kinase 6; p21-activated kinase 6

NP_001126024.1

EC 2.7.11.1

XP_054387082.1

EC 2.7.11.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001132552.1 → NP_001126024.1 serine/threonine-protein kinase PAK 6

See identical proteins and their annotated locations for NP_001126024.1

Status: PROVISIONAL

Source sequence(s)

CR859603

UniProtKB/Swiss-Prot

Q5R8Z4

UniProtKB/TrEMBL

A0A2J8T317, A0A8I5TYU1

Related

ENSPPYP00000007186.1, ENSPPYT00000007485.2

Conserved Domains (2) summary

cd06659
Location:385 → 681

STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

pfam00786
Location:11 → 67

PBD; P21-Rho-binding domain