GCHFR GTP cyclohydrolase I feedback regulator [Sus scrofa (pig)] - Gene

Summary

Gene symbol: GCHFR
Gene description: GTP cyclohydrolase I feedback regulator
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Ubiquitous expression in liver (RPKM 35.1), spleen (RPKM 27.9) and 8 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	1	NC_010443.5 (130559223..130563598, complement)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	1	NC_010443.4 (145717595..145721973, complement)

Chromosome 1 - NC_010443.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables GTP cyclohydrolase binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in negative regulation of GTP cyclohydrolase I activity	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: GTP cyclohydrolase 1 feedback regulatory protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001243443.1 → NP_001230372.1 GTP cyclohydrolase 1 feedback regulatory protein

See identical proteins and their annotated locations for NP_001230372.1

Status: VALIDATED

Source sequence(s)

AK346059

UniProtKB/TrEMBL

A0A4X1UVQ7

Conserved Domains (1) summary

pfam06399
Location:3 → 83

GFRP; GTP cyclohydrolase I feedback regulatory protein (GFRP)