U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

LATS1 large tumor suppressor kinase 1 [ Sus scrofa (pig) ]

Gene ID: 100152165, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
LATS1provided by VGNC
Official Full Name
large tumor suppressor kinase 1provided by VGNC
Primary source
VGNC:VGNC:89648
See related
Ensembl:ENSSSCG00000004106
Gene type
protein coding
RefSeq status
MODEL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in kidney (RPKM 7.3), lung (RPKM 6.8) and 8 other tissues See more
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (16274955..16320980)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (18600766..18633991)

Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene LDL receptor related protein 11 Neighboring gene protein-L-isoaspartate (D-aspartate) O-methyltransferase Neighboring gene nucleoporin 43 Neighboring gene katanin catalytic subunit A1 Neighboring gene glycosylated integral membrane protein 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  2. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hippo signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of organ growth IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
serine/threonine-protein kinase LATS1
Names
LATS, large tumor suppressor, homolog 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

    Range
    16274955..16320980
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005659149.3 → XP_005659206.2  serine/threonine-protein kinase LATS1

    UniProtKB/TrEMBL
    A0A4X1VQA5, A0A8D1C3H6, A0A8D1SGY1, F1S7T4
    Related
    ENSSSCP00000004439.3, ENSSSCT00000004541.5
    Conserved Domains (3) summary
    cd14397
    Location:101 → 141
    UBA_LATS1; UBA domain found in vertebrate serine/threonine-protein kinase LATS1
    cd05625
    Location:700 → 1081
    STKc_LATS1; Catalytic domain of the Serine/Threonine Kinase, Large Tumor Suppressor 1
    cl28087
    Location:423 → 592
    FtsK; DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell cycle control, cell division, chromosome partitioning]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Miscellaneous