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    HDAC5 histone deacetylase 5 [ Homo sapiens ]

    Gene ID: 10014, updated on 12-May-2012

    Summary

    Official Symbol
    HDAC5provided by HGNC
    Official Full Name
    histone deacetylase 5provided by HGNC
    Primary source
    HGNC:14068
    See related
    Ensembl:ENSG00000108840; HPRD:09246; MIM:605315
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    HD5; NY-CO-9; FLJ90614
    Summary
    Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

    Genomic context

    Location :
    17q21
    Sequence :
    Chromosome: 17; NC_000017.10 (42154121..42201014, complement)
    See HDAC5 in Epigenomics, MapViewer

    Chromosome 17 - NC_000017.10Genomic Context describing neighboring genes Neighboring gene LSM12 homolog (S. cerevisiae) Neighboring gene glucose 6 phosphatase, catalytic, 3 Neighboring gene chromosome 17 open reading frame 53 Neighboring gene chromosome 17 open reading frame 65 Neighboring gene ankyrin repeat and SOCS box containing 16

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    Q9UQL6 Q9H9E1 ANKRA2    HPRD  PubMed  
    Q9UQL6 Q6UB99 ANKRD11    HPRD  PubMed  
    Q9UQL6 P41182 BCL6    HPRD  PubMed  
    Q9UQL6 Q6W2J9 BCOR    HPRD  PubMed  
    Q9UQL6 Q9HCU9 BRMS1    HPRD  PubMed  
    Q9UQL6 Q14012 CAMK1    HPRD  PubMed  
    Q9UQL6 O94983 CAMTA2    HPRD  PubMed  
    Q9UQL6 P45973 CBX5    HPRD  PubMed  
    Q9UQL6 P33076 CIITA    HPRD  PubMed  
    Q9UQL6 Q9UHI6 DDX20    HPRD  PubMed  
    Q9UQL6 P26641 EEF1G    HPRD  PubMed  
    Q9UQL6 O95166 GABARAP    HPRD  PubMed  
    Q9UQL6 P15976 GATA1    HPRD  PubMed  
    Q9UQL6 P23769 GATA2    HPRD  PubMed  
    Q9UQL6 Q9NP62 GCM1    HPRD  PubMed  
    Q9UQL6 P62873 GNB1    HPRD  PubMed  
    Q9UQL6 O15379 HDAC3    HPRD  PubMed  
    Q9UQL6 Q9UQL6 HDAC5    HPRD  PubMed  
    Q9UQL6 O43593 HR    HPRD  PubMed  
    Q9UQL6 O43474 KLF4    HPRD  PubMed  
    Q9UQL6 Q02078 MEF2A    HPRD  PubMed  
    Q9UQL6 Q06413 MEF2C    HPRD  PubMed  
    Q9UQL6 Q14814 MEF2D    HPRD  PubMed  
    Q9UQL6 O75376 NCOR1    HPRD  PubMed  
    Q9UQL6 Q9Y618 NCOR2    HPRD  PubMed  
    Q9UQL6 Q00653 NFKB2    HPRD  PubMed  
    Q9UQL6 P48552 NRIP1    HPRD  PubMed  
    Q9UQL6 Q99623 PHB2    HPRD  PubMed  
    Q9UQL6 Q15139 PRKD1    HPRD  PubMed  
    Q9UQL6 O14593 RFXANK    HPRD  PubMed  
    Q9UQL6 Q13761 RUNX3    HPRD  PubMed  
    Q9UQL6 P31947 SFN    HPRD  PubMed  
    Q9UQL6 O43463 SUV39H1    HPRD  PubMed  
    Q9UQL6 P62988 UBB    HPRD  PubMed  
    Q9UQL6 P31946 YWHAB    HPRD  PubMed  
    Q9UQL6 P62258 YWHAE    HPRD  PubMed  
    Q9UQL6 Q05516 ZBTB16    HPRD  PubMed  
    BioGRID:115331 BioGRID:106556 ACAT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106563 ACLY    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106596 ACTN4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106617 ADAR    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106696 AHCY    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:121558 AHRR    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:111790 ALDH18A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106728 ALDOA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:121758 ANKRA2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:115331 BioGRID:106831 APLP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106966 ATP1A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106978 ATP2A2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106987 ATP5A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106994 ATP5B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:247278 Adrbk1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:114908 BAG2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107076 BCL6    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:121961 BCORL1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:107169 C1QBP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107243 CAD    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114106 CAMK1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:107265 CAMK2A    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:116744 CAMTA2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:120937 CAND1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107271 CANX    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:117030 CBX5    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:115827 CCT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113054 CCT3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115826 CCT4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116603 CCT5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107346 CCT6A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115825 CCT7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115933 CCT8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107424 CDC5L    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107420 CDK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110416 CIITA    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:107572 CKB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107579 CKMT1B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107623 CLTC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107710 COPB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114693 COPB2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107818 CS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107821 CSE1L    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107841 CSNK2A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107869 CTBP1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:115331 BioGRID:107984 DARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108009 DDB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108017 DDOST    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108019 DDX1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115776 DDX17    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116387 DDX20    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113649 DDX39B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108020 DDX3X    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:119375 DDX47    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108029 DHX15    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108025 DHX9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109534 DNAJA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:119699 DNAJB11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114596 DYRK1B    BioGRID  PubMed Biochemical Activity 
    BioGRID:115331 BioGRID:108220 ECH1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108257 EEF1G    BioGRID  PubMed Affinity Capture-MS; Two-hybrid 
    BioGRID:115331 BioGRID:114749 EFTUD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114211 EIF3B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114212 EIF3C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114214 EIF3F    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:119516 EIF3L    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108289 EIF4A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115119 EIF4A3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108325 EMD    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108372 EPRS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108403 ESR1    BioGRID  PubMed Reconstituted Complex 
    BioGRID:115331 BioGRID:108409 ETFA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108488 FASN    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108605 FLNA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113760 FXR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116465 GABARAP    BioGRID  PubMed Two-hybrid 
    BioGRID:115331 BioGRID:116802 GANAB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108893 GATA1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:108894 GATA2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:108895 GATA3    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:114093 GCM1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:116181 GCN1L1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109008 GLUD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109044 GNB1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:109068 GOT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109132 GPS2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:109272 H3F3A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109280 HADHA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109304 HCFC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109315 HDAC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114368 HDAC3    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:115106 HDAC4    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:115331 HDAC5    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:119613 HDAC7    BioGRID  PubMed Reconstituted Complex 
    BioGRID:115331 BioGRID:109338 HIF1A    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:109261 HIST1H1C    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:124439 HIST1H2BK    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113934 HIST2H2AC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113895 HIST3H3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:125732 HIST4H4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109420 HNRNPA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109422 HNRNPA2B1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:128670 HNRNPA3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109425 HNRNPD    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109426 HNRNPF    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109429 HNRNPH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109432 HNRNPL    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115530 HNRNPR    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:124985 HNRPLL    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109467 HOXC11    BioGRID  PubMed Two-hybrid 
    BioGRID:115331 BioGRID:120917 HR    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:109278 HSD17B10    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109552 HSP90AA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109558 HSP90AB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113036 HSP90B1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109535 HSPA1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109540 HSPA4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109541 HSPA5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109545 HSPA9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109561 HSPD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109605 IARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115886 IGF2BP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115604 IKZF1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:116485 IKZF2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:116484 IKZF3    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:122146 IKZF4    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:109821 ILF2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109822 ILF3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109828 IMPDH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114048 IRS4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:121775 KIAA1967    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114726 KLF4    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:110035 KPNB1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:119584 LARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110131 LDHA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110150 LGALS3BP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115432 LRPPRC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110226 LTA4H    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:117264 MAFF    BioGRID  PubMed Two-hybrid 
    BioGRID:115331 BioGRID:110304 MAP1B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110310 MARK3    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:110311 MARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110339 MCM2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110340 MCM3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110341 MCM4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110342 MCM5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110343 MCM6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110344 MCM7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110356 MDH2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110369 MEF2A    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:110372 MEF2C    BioGRID  PubMed Reconstituted Complex 
    BioGRID:115331 BioGRID:110373 MEF2D    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:114652 MTA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110622 MTHFD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:119124 MYEF2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:110712 MYH9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114973 NCOR1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:114974 NCOR2    BioGRID  PubMed Affinity Capture-MS; Reconstituted Complex; Two-hybrid 
    BioGRID:115331 BioGRID:110831 NEU1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110845 NFATC1    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity 
    BioGRID:115331 BioGRID:110857 NFKB1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:110859 NFKBIA    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:110861 NFKBIE    BioGRID  PubMed Reconstituted Complex 
    BioGRID:115331 BioGRID:114516 NFS1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110894 NME1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110904 NONO    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110902 NOP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114897 NPEPPS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110929 NPM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112956 NR2E1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:113843 NRIP1    BioGRID  PubMed Co-localization; Reconstituted Complex 
    BioGRID:115331 BioGRID:115950 NUDC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110980 NUMA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113717 NUP214    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:115041 NUP93    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110996 OAT    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114049 OGT    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111073 P4HB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111075 PA2G4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:117939 PABPC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106652 PARP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111127 PCBP2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111141 PCMT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111142 PCNA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115434 PDIA6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:128154 PGAM5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111251 PGK1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111264 PHB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116459 PHB2    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:117618 PHGDH    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111332 PKM2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111571 PKN1    BioGRID  PubMed Biochemical Activity 
    BioGRID:115331 BioGRID:111572 PKN2    BioGRID  PubMed Affinity Capture-MS; Biochemical Activity 
    BioGRID:115331 BioGRID:111474 PPIA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111493 PPP1CA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111507 PPP2CA    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:111508 PPP2CB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111510 PPP2R1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111512 PPP2R2A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:120946 PPP2R2D    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116136 PRDX3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115800 PRDX4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114956 PRDX6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111551 PRKAB1    BioGRID  PubMed Affinity Capture-Western; Biochemical Activity 
    BioGRID:115331 BioGRID:111566 PRKCD    BioGRID  PubMed Biochemical Activity 
    BioGRID:115331 BioGRID:111573 PRKD1    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:117384 PRKD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:117199 PRKD3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111577 PRKDC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:109512 PRMT1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115688 PRMT5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:118151 PRPF19    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:120347 PRPF39    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115842 PRPF8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111659 PSMA5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111666 PSMB5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111677 PSMC4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111678 PSMC5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111679 PSMC6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111680 PSMD1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111689 PSMD11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111681 PSMD2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111682 PSMD3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115195 PSMD6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111697 PTBP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111797 QARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115417 RAD50    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111837 RAN    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111852 RARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111863 RBBP4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111866 RBBP7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115700 RBM14    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:121843 RBM25    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114952 RBM39    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:118134 RBMX    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111910 REST    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:114180 RFXANK    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:971427 RL2    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:110813 RPL10A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112057 RPL13    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112042 RPL3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112044 RPL4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112045 RPL5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112049 RPL7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112050 RPL7A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112053 RPL9    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112094 RPLP0    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112099 RPN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112100 RPN2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112119 RPS11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112102 RPS3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112103 RPS3A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112105 RPS4X    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112116 RPS8    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:110115 RPSA    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:107308 RUNX2    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:114166 RUVBL1    BioGRID  PubMed Affinity Capture-MS 
    NP_006657.1 RUVBL2    BIND  PubMed RUVBL2 (reptin) interacts with an unspecified isoform of HDAC5. 
    BioGRID:115331 BioGRID:116067 RUVBL2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113368 SF1    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:115580 SF3A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:117017 SF3B1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116188 SF3B2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:117016 SF3B3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112319 SFPQ    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:125107 SFXN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112368 SHMT2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:117439 SIN3A    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:112464 SLC25A1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113990 SLC25A11    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:111269 SLC25A3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:106790 SLC25A6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:121193 SLC2A4RG    BioGRID  PubMed Reconstituted Complex 
    BioGRID:115331 BioGRID:110263 SMAD3    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 
    BioGRID:115331 BioGRID:110267 SMAD7    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:113871 SMC1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:114574 SMC3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116661 SNRNP200    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112324 SRSF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116342 STRAP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112706 SUV39H1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:116740 TAB2    BioGRID  PubMed Reconstituted Complex 
    BioGRID:115331 BioGRID:112760 TARS    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112770 TBL1X    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:122834 TBL1XR1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112788 TBX3    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:112810 TCP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112895 TFRC    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:112941 TKT    BioGRID  PubMed Affinity Capture-MS 
    NC_000003.9 TNFSF10    BIND  PubMed An unspecifed isoform of HDAC5 interacts with the TNFSF10 promoter. 
    BioGRID:115331 BioGRID:110040 TNPO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113003 TOP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113010 TP53    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113020 TPI1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115435 TRAP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115457 TRIM28    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113603 TUBA1A    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:128444 TUBB    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:115656 TUBB4B    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113135 TUFM    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113165 UBA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113177 UBE2I    BioGRID  PubMed Two-hybrid 
    BioGRID:115331 BioGRID:111908 UPF1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113231 UQCRC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113622 USP7    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113867 USP9X    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113258 VCP    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113259 VDAC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113260 VDAC2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116272 WDR5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113348 XPO1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116420 XPOT    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113353 XRCC5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:108822 XRCC6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113361 YWHAB    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:113363 YWHAE    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:113364 YWHAG    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western 
    BioGRID:115331 BioGRID:113365 YWHAH    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:116168 YWHAQ    BioGRID  PubMed Affinity Capture-MS; Affinity Capture-Western; Two-hybrid 
    BioGRID:115331 BioGRID:113366 YWHAZ    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:115331 BioGRID:113360 YY1    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:248364 Ywhae    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:115331 BioGRID:113498 ZBTB16    BioGRID  PubMed Affinity Capture-Western; Reconstituted Complex 

    General gene information

    Markers

    Homology

    Pathways from BioSystems

    • Alcoholism, organism-specific biosystem (from KEGG)
      Alcoholism, organism-specific biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
    • Alcoholism, conserved biosystem (from KEGG)
      Alcoholism, conserved biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
    • B Cell Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
      B Cell Receptor Signaling Pathway, organism-specific biosystemThe B cell receptor includes membrane ?? heavy chain molecules bound to a light chain and an Ig alpha (CD79A)/Ig beta (CD79B) heterodimer. Activation of the B cell receptor involves phosphorylation o...
    • Cell cycle, organism-specific biosystem (from WikiPathways)
      Cell cycle, organism-specific biosystem(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle in...
    • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
      Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Epstein-Barr virus infection, conserved biosystem (from KEGG)
      Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem (from WikiPathways)
      MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystemThis pathway shows the role of microRNAs in the process of cardiac hypertrophy. MicroRNA targets were predicted by the TargetScan algorithm, and the predicted interactions are shown in red dashed lin...
    • NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem (from REACTOME)
      NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystemNICD1 produced by activation of NOTCH1 in response to Delta and Jagged ligands (DLL/JAG) presented in trans, traffics to the nucleus where it acts as a transcription regulator. In the nucleus, NICD1 ...
    • Signal Transduction, organism-specific biosystem (from REACTOME)
      Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
    • Signaling by NOTCH, organism-specific biosystem (from REACTOME)
      Signaling by NOTCH, organism-specific biosystemThe Notch Signaling Pathway (NSP) is a highly conserved pathway for cell-cell communication. NSP is involved in the regulation of cellular differentiation, proliferation, and specification. For exam...
    • Signaling by NOTCH1, organism-specific biosystem (from REACTOME)
      Signaling by NOTCH1, organism-specific biosystemNOTCH1 functions as both a transmembrane receptor presented on the cell surface and as a transcriptional regulator in the nucleus.NOTCH1 receptor presented on the plasma membrane is activated by a me...
    • Signaling events mediated by HDAC Class I, organism-specific biosystem (from Pathway Interaction Database)
      Signaling events mediated by HDAC Class I, organism-specific biosystem
      Signaling events mediated by HDAC Class I
    • Signaling events mediated by HDAC Class II, organism-specific biosystem (from Pathway Interaction Database)
      Signaling events mediated by HDAC Class II, organism-specific biosystem
      Signaling events mediated by HDAC Class II

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    NAD-dependent histone deacetylase activity (H3-K14 specific) IEA
    Inferred from Electronic Annotation
    more info
     
    NAD-dependent histone deacetylase activity (H3-K9 specific) IEA
    Inferred from Electronic Annotation
    more info
     
    NAD-dependent histone deacetylase activity (H4-K16 specific) IEA
    Inferred from Electronic Annotation
    more info
     
    histone deacetylase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone deacetylase activity (H3-K16 specific) IEA
    Inferred from Electronic Annotation
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase C binding IPI
    Inferred from Physical Interaction
    more info
     
    repressing transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    contributes_to transcription regulatory region DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    B cell activation TAS
    Traceable Author Statement
    more info
    PubMed 
    B cell differentiation TAS
    Traceable Author Statement
    more info
    PubMed 
    cellular response to insulin stimulus NAS
    Non-traceable Author Statement
    more info
    PubMed 
    chromatin modification TAS
    Traceable Author Statement
    more info
    PubMed 
    chromatin organization TAS
    Traceable Author Statement
    more info
    PubMed 
    chromatin remodeling TAS
    Traceable Author Statement
    more info
    PubMed 
    chromatin silencing TAS
    Traceable Author Statement
    more info
    PubMed 
    histone deacetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone deacetylation TAS
    Traceable Author Statement
    more info
    PubMed 
    inflammatory response TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of cell migration involved in sprouting angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of myotube differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription, DNA-dependent TAS
    Traceable Author Statement
    more info
    PubMed 
    positive regulation of sequence-specific DNA binding transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of myotube differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of protein binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone deacetylase complex TAS
    Traceable Author Statement
    more info
    PubMed 
    NOT nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    histone deacetylase 5
    Names
    histone deacetylase 5
    antigen NY-CO-9
    NP_001015053.1
    NP_005465.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015053.1NP_001015053.1  histone deacetylase 5 isoform 3

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) represents the longer transcript and encodes the longer isoform (3).
      Source sequence(s)
      AB011172, AC023855, BC051824, CN290533
      Consensus CDS
      CCDS32663.1
      UniProtKB/Swiss-Prot
      Q9UQL6
      Related
      ENSP00000225983, ENST00000225983
      Conserved Domains (2) summary
      COG0123
      Location:6841034
      Blast Score: 545
      AcuC; Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]
      cl02986
      Location:6991024
      Blast Score: 813
      Hist_deacetyl; Histone deacetylase domain
    2. NM_005474.4NP_005465.2  histone deacetylase 5 isoform 1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) uses an alternate in-frame splice site compared to variant 3. The resulting isoform (1) has the same N- and C-termini but is 1 aa shorter compared to isoform 3.
      Source sequence(s)
      AB011172, AC023855, BC051824, BM564861, CN290533
      Consensus CDS
      CCDS45696.1
      UniProtKB/Swiss-Prot
      Q9UQL6
      Related
      ENSP00000377244, ENST00000393622
      Conserved Domains (2) summary
      COG0123
      Location:6831033
      Blast Score: 545
      AcuC; Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]
      cl02986
      Location:6981023
      Blast Score: 813
      Hist_deacetyl; Histone deacetylase domain

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000017.10 Reference GRCh37.p5 Primary Assembly

      Range
      42154121..42201014, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000149.1 Alternate HuRef

      Range
      37918049..37965007, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_139205.1: Suppressed sequence

      Description
      NM_139205.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.

    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AC023855.15 (11860..58753) None
    genomic BK000028.1 DAA00017.1
    genomic CH471178.2 EAW51633.1
      EAW51634.1
    mRNA AB011172.2 BAA25526.2
    mRNA AB177853.1 BAD66831.1
    mRNA AF039691.1 AAC18040.1
    mRNA AF132608.1 AAD29047.1
    mRNA AK027734.1 BAB55329.1
    mRNA AK075095.1 None
    mRNA AK093150.1 None
    mRNA AK294760.1 BAG57895.1
    mRNA BC011260.2 None
    mRNA BC013140.1 AAH13140.1
    mRNA BC038423.1 None
    mRNA BC041914.1 None
    mRNA BC051824.1 AAH51824.1
    mRNA BM564861.1 None
    mRNA BM998071.1 None
    mRNA CN290533.1 None
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5W9G6 GenPept UniProtKB/TrEMBL:Q5W9G6
    Q96K29 GenPept UniProtKB/TrEMBL:Q96K29
    Q9UQL6.2 GenPept UniProtKB/Swiss-Prot:Q9UQL6

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