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    Htr2a 5-hydroxytryptamine (serotonin) receptor 2A [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100135545, updated on 20-Feb-2013
    Gene symbol
    Htr2a
    Gene description
    5-hydroxytryptamine (serotonin) receptor 2A
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricognathi; Caviidae; Cavia
    Also known as
    5HT2
    Location :
    chromosome: Un
    See Htr2a in MapViewer

    NT_176413.1Genomic Context describing neighboring genes Neighboring gene leucine-rich repeat and calponin homology domain-containing protein 1-like Neighboring gene S-formylglutathione hydrolase-like Neighboring gene aurora kinase A-like Neighboring gene succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial-like

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. Role of 5-HT2A, 5-HT4 and 5-HT7 receptors in the antigen-induced airway hyperresponsiveness in guinea-pigs. Segura P, et al. Clin Exp Allergy, 2010 Feb. PMID 19995401.
    2. Disruption of potential alpha-helix in the G loop of the guinea pig 5-hydroxytryptamine2 receptor does not prevent receptor coupling to phosphoinositide hydrolysis. Watts SW, et al. J Neurochem, 1994 Mar. PMID 8113814.

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. The 5-HT 2A receptor seem to be particularly involved in antigen-induced airway hyperresponsiveness(AI-AHR) to ACh in guinea-pigs.
      Title: Role of 5-HT2A, 5-HT4 and 5-HT7 receptors in the antigen-induced airway hyperresponsiveness in guinea-pigs.
    Submit: New GeneRIF Correction

    Markers

    Names
    5-hydroxytryptamine (serotonin) receptor 2A
    serotonin 2 receptor

    RefSeqs of Annotated Genomes: Build 1.1

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Cavpor3.0 Primary Assembly

    Genomic

    1. NT_176413.1

      Range
      56840919..56906577, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003477480.1 → XP_003477528.1  

      UniProtKB/TrEMBL
      H0V043
      Conserved Domains (2) summary
      pfam00001
      Location:96 – 379
      Blast Score: 516
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl10458
      Location:88 – 206
      Blast Score: 116
      7tm_4; Olfactory receptor
    Nucleotide Protein
    Heading Accession and Version
    genomic AAKN02011140.1 (8576..23071) None
    genomic AAKN02011141.1 None
    genomic AAKN02011142.1 None
    mRNA M85162.1 AAA21022.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    P35382.1 GenPept UniProtKB/Swiss-Prot:P35382

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

      Supplemental Content

      Table of contents

      Related information

      • BioProjects
        BioProjects related to a gene
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Map Viewer
        These links are maintained by the Map Viewer group and are provided when a GeneID is annotated on a map for the same species.
      • Nucleotide
        Link to related Nucleotide entry
      • Probe
        Related Probe entry
      • Protein
        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed (GeneRIF)
        GeneRIF -- Gene Reference Into Function Staff of the Index Section in the National Library of Medicine review the current literature. When they find articles focused on the structure and function of a gene, they write a brief summary of the impact of the paper and make the connection between the citation (PubMed) and Gene. An interface exists for interested users to submit such data as well. http://www.ncbi.nlm.nih.gov/projects/GeneRIF/GeneRIFhelp.html
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • Taxonomy
        Link to related taxonomy entry
      • UniSTS
        Related UniSTS records

      Links to other resources

      General information

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