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MIR708 microRNA 708 [ Homo sapiens (human) ]

Gene ID: 100126333, updated on 26-May-2016
Official Symbol
MIR708provided by HGNC
Official Full Name
microRNA 708provided by HGNC
Primary source
HGNC:HGNC:33654
See related
Ensembl:ENSG00000211997 miRBase:MI0005543
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIRN708; hsa-mir-708
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Location:
11q14.1
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 11 NC_000011.10 (79402022..79402109, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (79113066..79113153, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369403 Neighboring gene asparaginyl-tRNA synthetase 2, mitochondrial (putative) Neighboring gene uncharacterized LOC101928896 Neighboring gene teneurin transmembrane protein 4 Neighboring gene uncharacterized LOC105369404 Neighboring gene microRNA 5579

Related articles in PubMed

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_030598.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AP001838
    Related
    ENST00000390708

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p2 Primary Assembly

    Range
    79402022..79402109 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018922.2 Alternate CHM1_1.1

    Range
    78995903..78995990 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)