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MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase [ Sus scrofa (pig) ]

Gene ID: 100125959, updated on 26-May-2016
Gene symbol
MDM2
Gene description
MDM2 proto-oncogene, E3 ubiquitin protein ligase
See related
Ensembl:ENSSSCG00000000488
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
Orthologs
Location:
5; 5
Exon count:
13
Annotation release Status Assembly Chr Location
105 current Sscrofa10.2 (GCF_000003025.5) 5 NC_010447.4 (35889682..35921569)

Chromosome 5 - NC_010447.4Genomic Context describing neighboring genes Neighboring gene nucleoporin 107kDa Neighboring gene solute carrier family 35, member E3 Neighboring gene carboxypeptidase M Neighboring gene uncharacterized LOC106510333

Genomic Sequence:
NC_010447.4 Chromosome 5 Reference Sscrofa10.2 Primary Assembly

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Preferred Names
E3 ubiquitin-protein ligase Mdm2
Names
Mdm2 p53 binding protein homolog
Mdm2, p53 E3 ubiquitin protein ligase homolog
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein
double minute 2
NP_001098773.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105303.1NP_001098773.1  E3 ubiquitin-protein ligase Mdm2

    See identical proteins and their annotated locations for NP_001098773.1

    Status: PROVISIONAL

    Source sequence(s)
    EU119401
    UniProtKB/TrEMBL
    A7Y496
    Related
    ENSSSCP00000000518, ENSSSCT00000000526
    Conserved Domains (3) summary
    cd00162
    Location:438482
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00641
    Location:299327
    zf-RanBP; Zn-finger in Ran binding protein and others
    pfam02201
    Location:40100
    SWIB; SWIB/MDM2 domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa10.2 Primary Assembly

Genomic

  1. NC_010447.4 Reference Sscrofa10.2 Primary Assembly

    Range
    35889682..35921569
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013997706.1XP_013853160.1  

    UniProtKB/TrEMBL
    F1SH62
    Conserved Domains (3) summary
    cd00162
    Location:438482
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00641
    Location:299327
    zf-RanBP; Zn-finger in Ran binding protein and others
    pfam02201
    Location:40100
    SWIB; SWIB/MDM2 domain
  2. XM_013997707.1XP_013853161.1  

    Conserved Domains (3) summary
    cd00162
    Location:415459
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00641
    Location:276304
    zf-RanBP; Zn-finger in Ran binding protein and others
    pfam02201
    Location:1777
    SWIB; SWIB/MDM2 domain
  3. XM_005663965.2XP_005664022.1  

    Conserved Domains (3) summary
    cd00162
    Location:377421
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00641
    Location:238266
    zf-RanBP; Zn-finger in Ran binding protein and others
    cl02489
    Location:139
    SWIB; SWIB/MDM2 domain
  4. XM_005663964.2XP_005664021.1  

    Conserved Domains (3) summary
    cd00162
    Location:389433
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam00641
    Location:250278
    zf-RanBP; Zn-finger in Ran binding protein and others
    pfam02201
    Location:151
    SWIB; SWIB/MDM2 domain