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GCH1 GTP cyclohydrolase 1 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100091019, updated on 8-Mar-2024

Summary

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Gene symbol
GCH1
Gene description
GTP cyclohydrolase 1
See related
Ensembl:ENSOANG00000011384
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 14
Exon count:
6
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 14 NC_041741.1 (2811263..2835432)

Chromosome 14 - NC_041741.1Genomic Context describing neighboring genes Neighboring gene suppressor of cytokine signaling 4 Neighboring gene WD repeat and HMG-box DNA binding protein 1 Neighboring gene sterile alpha motif domain containing 4A Neighboring gene cell growth regulator with ring finger domain 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041741.1 Chromosome 14 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP cyclohydrolase I activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrobiopterin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GTP cyclohydrolase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041741.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    2811263..2835432
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029079293.2 → XP_028935126.1  GTP cyclohydrolase 1

    UniProtKB/TrEMBL
    F6T6D2
    Related
    ENSOANP00000018040.2
    Conserved Domains (1) summary
    cd00642
    Location:29 → 210
    GTP_cyclohydro1; GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate. The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria. In ...
Nucleotide Protein
Heading Accession and Version

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