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PLEKHM2 pleckstrin homology and RUN domain containing M2 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100078780, updated on 8-Mar-2024

Summary

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Gene symbol
PLEKHM2
Gene description
pleckstrin homology and RUN domain containing M2
See related
Ensembl:ENSOANG00000005720
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 5
Exon count:
21
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 5 NC_041732.1 (63368343..63426504, complement)

Chromosome 5 - NC_041732.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 82 Neighboring gene solute carrier family 25 member 34 Neighboring gene protein DDI1 homolog 2 Neighboring gene small nucleolar RNA SNORA7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041732.1 Chromosome 5 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables kinesin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Golgi organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lysosome localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of membrane tubulation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of protein localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family M member 2
Names
pleckstrin homology domain containing, family M (with RUN domain) member 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041732.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    63368343..63426504 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029065738.2 → XP_028921571.1  pleckstrin homology domain-containing family M member 2 isoform X3

    Conserved Domains (2) summary
    smart00593
    Location:91 → 154
    RUN; domain involved in Ras-like GTPase signaling
    cd13309
    Location:781 → 883
    PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain

  2. XM_029065739.2 → XP_028921572.1  pleckstrin homology domain-containing family M member 2 isoform X4

    Conserved Domains (2) summary
    smart00593
    Location:93 → 156
    RUN; domain involved in Ras-like GTPase signaling
    cd13309
    Location:763 → 865
    PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain

  3. XM_029065736.2 → XP_028921569.1  pleckstrin homology domain-containing family M member 2 isoform X1

    Conserved Domains (2) summary
    smart00593
    Location:93 → 156
    RUN; domain involved in Ras-like GTPase signaling
    cd13309
    Location:783 → 885
    PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain

  4. XM_029065741.2 → XP_028921574.1  pleckstrin homology domain-containing family M member 2 isoform X6

    Conserved Domains (1) summary
    cd13309
    Location:618 → 720
    PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain

  5. XM_029065740.2 → XP_028921573.1  pleckstrin homology domain-containing family M member 2 isoform X5

    UniProtKB/TrEMBL
    A0A6I8P534
    Related
    ENSOANP00000049070.1
    Conserved Domains (2) summary
    smart00593
    Location:93 → 156
    RUN; domain involved in Ras-like GTPase signaling
    cd13309
    Location:763 → 865
    PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain

  6. XM_029065737.1 → XP_028921570.1  pleckstrin homology domain-containing family M member 2 isoform X2

    UniProtKB/TrEMBL
    F6XYL3
    Related
    ENSOANP00000009105.3, ENSOANT00000009107.3
    Conserved Domains (2) summary
    smart00593
    Location:93 → 156
    RUN; domain involved in Ras-like GTPase signaling
    cd13309
    Location:783 → 885
    PH_SKIP; SifA and kinesin-interacting protein Pleckstrin homology (PH) domain
Nucleotide Protein
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