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TIMP1 TIMP metallopeptidase inhibitor 1 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100075268, updated on 8-Mar-2024

Summary

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Gene symbol
TIMP1
Gene description
TIMP metallopeptidase inhibitor 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
7
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 6 NC_041733.1 (22624921..22628753, complement)

Chromosome 6 - NC_041733.1Genomic Context describing neighboring genes Neighboring gene serine/arginine repetitive matrix protein 1-like Neighboring gene complement factor properdin Neighboring gene synapsin I Neighboring gene A-Raf proto-oncogene, serine/threonine kinase Neighboring gene olfactory receptor 3A3-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041733.1 Chromosome 6 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protease binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to organic substance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metalloproteinase inhibitor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041733.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    22624921..22628753 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029067018.2 → XP_028922851.1  metalloproteinase inhibitor 1 isoform X2

    Conserved Domains (1) summary
    cl02512
    Location:25 → 202
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...

  2. XM_029067016.2 → XP_028922849.1  metalloproteinase inhibitor 1 isoform X1

    Conserved Domains (1) summary
    cl02512
    Location:36 → 213
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...
Nucleotide Protein
Heading Accession and Version

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