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LIMK2 LIM domain kinase 2 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100074515, updated on 8-Mar-2024

Summary

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Gene symbol
LIMK2
Gene description
LIM domain kinase 2
See related
Ensembl:ENSOANG00000014650
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 2 NC_041729.1 (23898484..23955142, complement)

Chromosome 2 - NC_041729.1Genomic Context describing neighboring genes Neighboring gene POZ/BTB and AT hook containing zinc finger 1 Neighboring gene uncharacterized LOC114807858 Neighboring gene phosphoinositide-3-kinase interacting protein 1 Neighboring gene ring finger protein 185 Neighboring gene chromosome 2 C12orf43 homolog

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041729.1 Chromosome 2 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LIM domain kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041729.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    23898484..23955142 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007672161.4 → XP_007670351.1  LIM domain kinase 2 isoform X1

    UniProtKB/TrEMBL
    A0A6I8N2M8, A0A6I8P2J7
    Related
    ENSOANP00000035147.1
    Conserved Domains (5) summary
    cd09465
    Location:69 → 127
    LIM2_LIMK2; The second LIM domain of LIMK2 (LIM domain Kinase 2)
    smart00221
    Location:336 → 603
    STYKc; Protein kinase; unclassified specificity
    cd14222
    Location:339 → 610
    STKc_LIMK2; Catalytic domain of the Serine/Threonine Kinase, LIM domain kinase 2
    pfam00595
    Location:154 → 238
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl02475
    Location:14 → 67
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  2. XM_029049479.2 → XP_028905312.1  LIM domain kinase 2 isoform X3

    UniProtKB/TrEMBL
    A0A6I8P2J7
    Conserved Domains (4) summary
    cd09465
    Location:42 → 100
    LIM2_LIMK2; The second LIM domain of LIMK2 (LIM domain Kinase 2)
    cd14222
    Location:312 → 583
    STKc_LIMK2; Catalytic domain of the Serine/Threonine Kinase, LIM domain kinase 2
    pfam00595
    Location:127 → 211
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl02475
    Location:11 → 40
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers

  3. XM_029049469.2 → XP_028905302.1  LIM domain kinase 2 isoform X2

    UniProtKB/TrEMBL
    A0A6I8P2J7, F7DST7
    Related
    ENSOANP00000023083.2
    Conserved Domains (4) summary
    cd09465
    Location:46 → 104
    LIM2_LIMK2; The second LIM domain of LIMK2 (LIM domain Kinase 2)
    cd14222
    Location:316 → 587
    STKc_LIMK2; Catalytic domain of the Serine/Threonine Kinase, LIM domain kinase 2
    pfam00595
    Location:131 → 215
    PDZ; PDZ domain (Also known as DHR or GLGF)
    cl02475
    Location:17 → 44
    LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
Nucleotide Protein
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