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EPHA7 EPH receptor A7 [ Ornithorhynchus anatinus (platypus) ]

Gene ID: 100073935, updated on 11-Apr-2024

Summary

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Gene symbol
EPHA7
Gene description
EPH receptor A7
See related
Ensembl:ENSOANG00000008930
Gene type
protein coding
RefSeq status
MODEL
Organism
Ornithorhynchus anatinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
19
Annotation release Status Assembly Chr Location
105 current mOrnAna1.pri.v4 (GCF_004115215.2) 19 NC_041746.1 (29871896..30044669, complement)

Chromosome 19 - NC_041746.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA SNORA7 Neighboring gene uncharacterized LOC114805679 Neighboring gene uncharacterized LOC114805722 Neighboring gene uncharacterized LOC103171148 Neighboring gene small nucleolar RNA SNORA7

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_041746.1 Chromosome 19 Reference mOrnAna1.pri.v4 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane-ephrin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ephrin type-A receptor 7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ornithorhynchus anatinus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrnAna1.pri.v4 Primary Assembly

Genomic

  1. NC_041746.1 Reference mOrnAna1.pri.v4 Primary Assembly

    Range
    29871896..30044669 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029047299.2 → XP_028903132.2  ephrin type-A receptor 7 isoform X8

    UniProtKB/TrEMBL
    F7D2V3
    Conserved Domains (4) summary
    cd09548
    Location:944 → 1013
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    cd10485
    Location:54 → 230
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:467 → 558
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:652 → 919
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors

  2. XM_029047301.1 → XP_028903134.1  ephrin type-A receptor 7 isoform X9

    UniProtKB/TrEMBL
    F7D2V3
    Conserved Domains (5) summary
    cd09548
    Location:840 → 909
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    cd00063
    Location:363 → 454
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:548 → 815
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam14575
    Location:485 → 548
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl02704
    Location:65 → 107
    EphR_LBD; Ligand Binding Domain of Ephrin Receptors

  3. XM_039914775.1 → XP_039770709.1  ephrin type-A receptor 7 isoform X7

    UniProtKB/TrEMBL
    F7D2V3
    Conserved Domains (4) summary
    cd09548
    Location:945 → 1014
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:654 → 920
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors

  4. XM_001506722.5 → XP_001506772.3  ephrin type-A receptor 7 isoform X6

    UniProtKB/TrEMBL
    F7D2V3
    Conserved Domains (7) summary
    cd09548
    Location:949 → 1018
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    smart00454
    Location:950 → 1017
    SAM; Sterile alpha motif
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:658 → 924
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:663 → 920
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:595 → 658
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  5. XM_029047297.1 → XP_028903130.1  ephrin type-A receptor 7 isoform X4

    UniProtKB/TrEMBL
    F7D2V3
    Conserved Domains (5) summary
    cd09548
    Location:950 → 1019
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:658 → 925
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam14575
    Location:595 → 658
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  6. XM_007671838.3 → XP_007670028.1  ephrin type-A receptor 7 isoform X5

    UniProtKB/TrEMBL
    F7D2V3
    Conserved Domains (7) summary
    cd09548
    Location:950 → 1019
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    smart00454
    Location:951 → 1018
    SAM; Sterile alpha motif
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:659 → 925
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:664 → 921
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:600 → 659
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  7. XM_029047296.1 → XP_028903129.1  ephrin type-A receptor 7 isoform X3

    UniProtKB/TrEMBL
    F7D2V3
    Conserved Domains (5) summary
    cd09548
    Location:951 → 1020
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:659 → 926
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam14575
    Location:600 → 659
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  8. XM_007671837.3 → XP_007670027.1  ephrin type-A receptor 7 isoform X2

    UniProtKB/TrEMBL
    F7D2V3
    Related
    ENSOANP00000014218.2, ENSOANT00000014221.3
    Conserved Domains (7) summary
    cd09548
    Location:954 → 1023
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    smart00454
    Location:955 → 1022
    SAM; Sterile alpha motif
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:663 → 929
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:668 → 925
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:600 → 663
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  9. XM_029047295.1 → XP_028903128.1  ephrin type-A receptor 7 isoform X1

    UniProtKB/TrEMBL
    F7D2V3
    Conserved Domains (5) summary
    cd09548
    Location:955 → 1024
    SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:663 → 930
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam14575
    Location:600 → 663
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  10. XM_039914776.1 → XP_039770710.1  ephrin type-A receptor 7 isoform X11

    Conserved Domains (3) summary
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl22855
    Location:300 → 357
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  11. XM_007671842.2 → XP_007670032.1  ephrin type-A receptor 7 isoform X10

    Conserved Domains (3) summary
    cd10485
    Location:65 → 241
    EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
    cd00063
    Location:478 → 569
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07699
    Location:310 → 347
    GCC2_GCC3; GCC2 and GCC3
Nucleotide Protein
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