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ROBO2 roundabout guidance receptor 2 [ Equus caballus (horse) ]

Gene ID: 100068957, updated on 8-Mar-2024

Summary

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Official Symbol
ROBO2provided by VGNC
Official Full Name
roundabout guidance receptor 2provided by VGNC
Primary source
VGNC:VGNC:22493
See related
Ensembl:ENSECAG00000010762
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See ROBO2 in Genome Data Viewer
Location:
chromosome: 26
Exon count:
31
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 26 NC_009169.3 (12245696..13454802, complement)
102 previous assembly EquCab2.0 (GCF_000002305.2) 26 NC_009169.2 (11748814..12312743, complement)

Chromosome 26 - NC_009169.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111770785 Neighboring gene uncharacterized LOC111770849 Neighboring gene uncharacterized LOC111770798 Neighboring gene calponin-3 pseudogene Neighboring gene lipase I Neighboring gene RNA binding motif protein 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
roundabout homolog 2
Names
roundabout, axon guidance receptor, homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009169.3 Reference EquCab3.0 Primary Assembly

    Range
    12245696..13454802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023630097.1 → XP_023485865.1  roundabout homolog 2 isoform X3

    UniProtKB/TrEMBL
    F7BHQ9
    Conserved Domains (5) summary
    cd05726
    Location:351 → 440
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:447 → 526
    IG_like; Immunoglobulin like
    cd00063
    Location:545 → 638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  2. XM_023630096.1 → XP_023485864.1  roundabout homolog 2 isoform X2

    UniProtKB/TrEMBL
    F7BHQ9
    Conserved Domains (5) summary
    cd05726
    Location:355 → 444
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:451 → 530
    IG_like; Immunoglobulin like
    cd00063
    Location:549 → 642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  3. XM_023630095.1 → XP_023485863.1  roundabout homolog 2 isoform X1

    UniProtKB/TrEMBL
    F7BHQ9
    Conserved Domains (5) summary
    cd05726
    Location:355 → 444
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:451 → 530
    IG_like; Immunoglobulin like
    cd00063
    Location:549 → 642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  4. XM_023630101.1 → XP_023485869.1  roundabout homolog 2 isoform X7

    UniProtKB/TrEMBL
    A0A3Q2LRY7
    Conserved Domains (5) summary
    cd05726
    Location:351 → 440
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:447 → 526
    IG_like; Immunoglobulin like
    cd00063
    Location:545 → 638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  5. XM_023630098.1 → XP_023485866.1  roundabout homolog 2 isoform X5

    UniProtKB/TrEMBL
    F7BHQ9
    Conserved Domains (5) summary
    cd05726
    Location:355 → 444
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:451 → 530
    IG_like; Immunoglobulin like
    cd00063
    Location:549 → 642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  6. XM_023630099.1 → XP_023485867.1  roundabout homolog 2 isoform X6

    UniProtKB/TrEMBL
    A0A3Q2LRY7
    Conserved Domains (5) summary
    cd05726
    Location:355 → 444
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:451 → 530
    IG_like; Immunoglobulin like
    cd00063
    Location:549 → 642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  7. XM_023630102.1 → XP_023485870.1  roundabout homolog 2 isoform X8

    UniProtKB/TrEMBL
    A0A3Q2I2I0
    Conserved Domains (5) summary
    cd05726
    Location:355 → 444
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00409
    Location:451 → 530
    IG; Immunoglobulin
    cd00063
    Location:549 → 642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  8. XM_023630103.1 → XP_023485871.1  roundabout homolog 2 isoform X9

    UniProtKB/TrEMBL
    A0A3Q2HFQ1
    Conserved Domains (5) summary
    cd05726
    Location:355 → 444
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:451 → 530
    IG_like; Immunoglobulin like
    cd00063
    Location:549 → 642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  9. XM_023630105.1 → XP_023485873.1  roundabout homolog 2 isoform X11

    UniProtKB/TrEMBL
    A0A3Q2HFQ1
    Related
    ENSECAP00000033371.3, ENSECAT00000059616.3
    Conserved Domains (5) summary
    cd05726
    Location:351 → 440
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:447 → 526
    IG_like; Immunoglobulin like
    cd00063
    Location:545 → 638
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  10. XM_023630104.1 → XP_023485872.1  roundabout homolog 2 isoform X10

    UniProtKB/TrEMBL
    A0A3Q2HFQ1
    Related
    ENSECAP00000041349.3, ENSECAT00000045003.3
    Conserved Domains (5) summary
    cd05726
    Location:355 → 444
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:53 → 152
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00409
    Location:451 → 530
    IG; Immunoglobulin
    cd00063
    Location:549 → 642
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl11960
    Location:160 → 244
    Ig; Immunoglobulin domain

  11. XM_014736310.2 → XP_014591796.1  roundabout homolog 2 isoform X4

    UniProtKB/TrEMBL
    F7BHQ9
    Related
    ENSECAP00000009128.4, ENSECAT00000011651.4
    Conserved Domains (7) summary
    cd00096
    Location:439 → 506
    Ig; Immunoglobulin domain
    cd05726
    Location:332 → 421
    Ig4_Robo; Third immunoglobulin (Ig)-like domain in Robo (roundabout) receptors
    cd07693
    Location:30 → 129
    Ig1_Robo; First immunoglobulin (Ig)-like domain in Robo (roundabout) receptors and similar proteins
    smart00410
    Location:428 → 507
    IG_like; Immunoglobulin like
    cd00063
    Location:526 → 619
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:225 → 310
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:137 → 221
    Ig; Immunoglobulin domain
Nucleotide Protein
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