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GYS2 glycogen synthase 2 (liver) [ Equus caballus (horse) ]

Gene ID: 100064264, updated on 24-Jan-2015
Gene symbol
GYS2
Gene description
glycogen synthase 2 (liver)
See related
Ensembl:ENSECAG00000014649
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
See GYS2 in MapViewer
Location:
chromosome: 6
Exon count:
16
Annotation release Status Assembly Chr Location
101 current EquCab2.0 (GCF_000002305.2) 6 NC_009149.2 (47742787..47795165, complement)

Chromosome 6 - NC_009149.2Genomic Context describing neighboring genes Neighboring gene golgi transport 1B Neighboring gene chromosome 6 open reading frame, human C12orf39 Neighboring gene lactate dehydrogenase B Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 8

Genomic Sequence:
NC_009149.2 chromosome 6 reference EquCab2.0 Primary Assembly

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • AMPK signaling pathway, organism-specific biosystem (from KEGG)
    AMPK signaling pathway, organism-specific biosystemAMP-activated protein kinase (AMPK) is a serine threonine kinase that is highly conserved through evolution. AMPK system acts as a sensor of cellular energy status. It is activated by increases in th...
  • AMPK signaling pathway, conserved biosystem (from KEGG)
    AMPK signaling pathway, conserved biosystemAMP-activated protein kinase (AMPK) is a serine threonine kinase that is highly conserved through evolution. AMPK system acts as a sensor of cellular energy status. It is activated by increases in th...
  • Glucagon signaling pathway, organism-specific biosystem (from KEGG)
    Glucagon signaling pathway, organism-specific biosystemGlucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase ...
  • Glucagon signaling pathway, conserved biosystem (from KEGG)
    Glucagon signaling pathway, conserved biosystemGlucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. To increase ...
  • Insulin signaling pathway, organism-specific biosystem (from KEGG)
    Insulin signaling pathway, organism-specific biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
  • Insulin signaling pathway, conserved biosystem (from KEGG)
    Insulin signaling pathway, conserved biosystemInsulin binding to its receptor results in the tyrosine phosphorylation of insulin receptor substrates (IRS) by the insulin receptor tyrosine kinase (INSR). This allows association of IRSs with the r...
  • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
    PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
    PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
  • Starch and sucrose metabolism, organism-specific biosystem (from KEGG)
    Starch and sucrose metabolism, organism-specific biosystem
    Starch and sucrose metabolism
  • Starch and sucrose metabolism, conserved biosystem (from KEGG)
    Starch and sucrose metabolism, conserved biosystem
    Starch and sucrose metabolism

RefSeqs of Annotated Genomes: Equus caballus Annotation Release 101

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab2.0 Primary Assembly

Genomic

  1. NC_009149.2 Reference EquCab2.0 Primary Assembly

    Range
    47742787..47795165
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005610971.1XP_005611028.1  

    Conserved Domains (2) summary
    pfam05693
    Location:32593
    Glycogen_syn; Glycogen synthase
    cl10013
    Location:27551
    Glycosyltransferase_GTB_type; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate ...
  2. XM_001502186.3XP_001502236.1  

    UniProtKB/TrEMBL
    F7DR61
    Related
    ENSECAP00000012864, ENSECAT00000015955
    Conserved Domains (2) summary
    cd03793
    Location:27615
    GT1_Glycogen_synthase_GSY2_like; Glycogen synthase, which is most closely related to the GT1 family of glycosyltransferases, catalyzes the transfer of a glucose molecule from UDP-glucose to a terminal branch of a glycogen molecule, a rate-limit step of glycogen biosynthesis. GSY2, the ...
    pfam05693
    Location:32657
    Glycogen_syn; Glycogen synthase