ABI1 abl-interactor 1 [Homo sapiens (human)] - Gene

Summary

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Official Symbol: ABI1provided by HGNC
Official Full Name: abl-interactor 1provided by HGNC
Primary source: HGNC:11320
Locus tag: RP13-16H11.4
See related: Ensembl:ENSG00000136754; HPRD:04336; MIM:603050; Vega:OTTHUMG00000017848
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: E3B1; ABI-1; ABLBP4; NAP1BP; SSH3BP; SSH3BP1
Summary: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]

Genomic context

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Location :: 10p11.2

Sequence :: Chromosome: 10; NC_000010.10 (27035525..27150016, complement)

See ABI1 in Epigenomics, MapViewer

Chromosome 10 - NC_000010.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

a possible role for Abi1 as a marker for early KRAS mutation in hyperplastic polyps
Title: Expression of Abelson interactor 1 (Abi1) correlates with inflammation, KRAS mutation and adenomatous change during colonic carcinogenesis.
Breast tumors expressing high levels of Abi1 are significantly associated with early recurrence and worse survival on multivariate analysis.
Title: Expression of Abl interactor 1 and its prognostic significance in breast cancer: a tissue-array-based investigation.
Down-regulation of E3B1/ABI-1 expression in human carcinomas may play a critical role in tumor progression and in determining disease prognosis.
Title: E3B1/ABI-1 isoforms are down-regulated in cancers of human gastrointestinal tract.
The phosphorylation and dephosphorylation cycle of VASP by the Abi-1-bridged mechanism regulates association of VASP with focal adhesions, which may regulate adhesion of Bcr-Abl-transformed leukaemic cells.
Title: Abl-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesion.
CDK1-mediated phosphorylation of Abi1 attenuates Bcr-Abl-induced F-actin assembly and tyrosine phosphorylation of WAVE complex during mitosis
Title: CDK1-mediated phosphorylation of Abi1 attenuates Bcr-Abl-induced F-actin assembly and tyrosine phosphorylation of WAVE complex during mitosis.
Expression of Abi1 is up-regulated in hepatocellular carcinoma tissues compared with corresponding para carcinomatous liver tissue, and is significantly correlated with tumor number, capsular formation, venous invasion, grade and prognosis.
Title: [Increased expression of Abi1 in hepatocellular carcinoma and its correlation with poor prognosis of hepatocellular carcinoma].
Data show that disruption of phosphorylation sits Y398 and Y213 significantly weakens the binding of Abi-1 to c-Abl.
Title: Identification and functional analysis of a new phosphorylation site (Y398) in the SH3 domain of Abi-1.
Study implicates that the integrity of SOS1/EPS8/ABI1 tri-complex is a determinant of ovarian cancer metastasis.
Title: Integrity of SOS1/EPS8/ABI1 tri-complex determines ovarian cancer metastasis.
Downregulation of ABI1 expression in human gastric carcinoma may play a critical role in tumor progression and in determining patient prognosis.
Title: Downregulation of ABI1 expression affects the progression and prognosis of human gastric carcinoma.
Macropinocytosis is regulated by interactions between Abi1 pY213 and the C-terminal SH2 domain of p85-thereby linking Abl kinase signaling to p85-dependent regulation of macropinocytosis.
Title: Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.

Submit: New GeneRIF Correction See all (33)

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Interactions

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Products	Interactant	Other Gene	Source	Pubs	Description
AAN28379.1	NP_000256.1	NCF1C	BIND	PubMed	ABI-1 interacts with p47phox.
BAB55675.1		ABL1	BIND	PubMed	hNap1BP interacts with Abl.
BAB55675.1	NP_038464.1	NCKAP1	BIND	PubMed	Nap1 interacts with hNap1BP.
NP_005461.1		DNM2	BIND	PubMed	An unspecified isoform of Dyn2 interacts with Abi-1. This interaction was modeled on a demonstrated interaction between human Dyn2 and Abi-1 from an unspecified species.
Q8IZP0	Q8IZP0	ABI1	HPRD	PubMed
Q8IZP0	P00519	ABL1	HPRD	PubMed
Q8IZP0	Q96F07	CYFIP2	HPRD	PubMed
Q8IZP0	Q8N8S7	ENAH	HPRD	PubMed
Q8IZP0	Q12929	EPS8	HPRD	PubMed
Q8IZP0	Q8TE68	EPS8L1	HPRD	PubMed
Q8IZP0	Q9UI08	EVL	HPRD	PubMed
Q8IZP0	P11142	HSPA8	HPRD	PubMed
Q8IZP0	Q8N4C8	MINK1	HPRD	PubMed
Q8IZP0	P14598	NCF1	HPRD	PubMed
Q8IZP0	P16333	NCK1	HPRD	PubMed
Q8IZP0	O43639	NCK2	HPRD	PubMed
Q8IZP0	Q9Y2A7	NCKAP1	HPRD	PubMed
Q8IZP0	P20929	NEB	HPRD	PubMed
Q8IZP0	Q8N4C6	NIN	HPRD	PubMed
Q8IZP0	Q13177	PAK2	HPRD	PubMed
Q8IZP0	Q07889	SOS1	HPRD	PubMed
Q8IZP0	Q07890	SOS2	HPRD	PubMed
Q8IZP0	P02549	SPTA1	HPRD	PubMed
Q8IZP0	Q13813	SPTAN1	HPRD	PubMed
Q8IZP0	P50552	VASP	HPRD	PubMed
Q8IZP0	Q92558	WASF1	HPRD	PubMed
Q8IZP0	Q8IV90	WASF2	HPRD	PubMed
BioGRID:115324	BioGRID:106543	ABL1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:115324	BioGRID:106819	APBB1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:115324	BioGRID:107227	CACNA1A	BioGRID	PubMed	Affinity Capture-Western; Two-hybrid
BioGRID:115324	BioGRID:107315	CBL	BioGRID	PubMed	Affinity Capture-Western
BioGRID:115324	BioGRID:114392	CDC123	BioGRID	PubMed	Co-fractionation
BioGRID:115324	BioGRID:108332	CTTN	BioGRID	PubMed	Co-fractionation
BioGRID:115324	BioGRID:120858	ENAH	BioGRID	PubMed	Reconstituted Complex; Two-hybrid
BioGRID:115324	BioGRID:108373	EPS8	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:115324	BioGRID:120218	EPS8L1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:115324	BioGRID:122297	EPS8L2	BioGRID	PubMed	Affinity Capture-Western
BioGRID:115324	BioGRID:122721	EPS8L3	BioGRID	PubMed	Affinity Capture-Western
BioGRID:115324	BioGRID:114094	GAS7	BioGRID	PubMed	Affinity Capture-MS
BioGRID:115324	BioGRID:110770	NCK1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:115324	BioGRID:114020	NCK2	BioGRID	PubMed	Affinity Capture-Western
BioGRID:115324	BioGRID:116003	NCKAP1	BioGRID	PubMed	Affinity Capture-Western; Two-hybrid
BioGRID:115324	BioGRID:111313	PIK3R1	BioGRID	PubMed	Affinity Capture-Western; Protein-peptide
BioGRID:115324	BioGRID:111549	PRKAA1	BioGRID	PubMed	Affinity Capture-Western
BioGRID:115324	BioGRID:120792	PRPF40A	BioGRID	PubMed	Affinity Capture-MS
BioGRID:115324	BioGRID:112171	RYK	BioGRID	PubMed	Affinity Capture-MS
BioGRID:115324	BioGRID:112537	SOS1	BioGRID	PubMed	Affinity Capture-Western; Reconstituted Complex
BioGRID:115324	BioGRID:115544	SRRM1	BioGRID	PubMed	Two-hybrid
BioGRID:115324	BioGRID:116120	TCERG1	BioGRID	PubMed	Affinity Capture-MS
BioGRID:115324	BioGRID:113164	UBC	BioGRID	PubMed	Affinity Capture-MS

Pathways from BioSystems

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E-cadherin signaling in the nascent adherens junction, organism-specific biosystem (from Pathway Interaction Database)
E-cadherin signaling in the nascent adherens junction, organism-specific biosystem
E-cadherin signaling in the nascent adherens junction
EGFR1 Signaling Pathway, organism-specific biosystem (from WikiPathways)
EGFR1 Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...
ErbB1 downstream signaling, organism-specific biosystem (from Pathway Interaction Database)
ErbB1 downstream signaling, organism-specific biosystem
ErbB1 downstream signaling
Fcgamma receptor (FCGR) dependent phagocytosis, organism-specific biosystem (from REACTOME)
Fcgamma receptor (FCGR) dependent phagocytosis, organism-specific biosystemPhagocytosis is one of the important innate immune responses that function to eliminate invading infectious agents. Monocytes, macrophages, and neutrophils are the professional phagocytic cells. Phag...
Immune System, organism-specific biosystem (from REACTOME)
Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
Innate Immune System, organism-specific biosystem (from REACTOME)
Innate Immune System, organism-specific biosystemInnate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup
RAC1 signaling pathway, organism-specific biosystem (from Pathway Interaction Database)
RAC1 signaling pathway, organism-specific biosystem
RAC1 signaling pathway
Regulation of RAC1 activity, organism-specific biosystem (from Pathway Interaction Database)
Regulation of RAC1 activity, organism-specific biosystem
Regulation of RAC1 activity
Regulation of actin dynamics for phagocytic cup formation, organism-specific biosystem (from REACTOME)
Regulation of actin dynamics for phagocytic cup formation, organism-specific biosystemThe actin cytoskeleton is fundamental for phagocytosis and members of the Rho family GTPases RAC and CDC42 are involved in actin cytoskeletal regulation leading to pseudopod extension. Active RAC and...
Stabilization and expansion of the E-cadherin adherens junction, organism-specific biosystem (from Pathway Interaction Database)
Stabilization and expansion of the E-cadherin adherens junction, organism-specific biosystem
Stabilization and expansion of the E-cadherin adherens junction

General gene information

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Markers

WI-15761 (e-PCR)
- UniSTS:83524

99-1126 (e-PCR)
- UniSTS:240718

D10S593 (e-PCR)
- UniSTS:80

RH121642 (e-PCR)
- UniSTS:134324

SHGC-142094 (e-PCR)
- UniSTS:171246

Homology

Homologs of the ABI1 gene: The ABI1 gene is conserved in chimpanzee, Rhesus monkey, dog, mouse, rat, chicken, and zebrafish.
Map Viewer (Mouse, Rat)
OrthoDB: The Hierarchical Catalog of Eukaryotic Orthologs

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
cytoskeletal protein binding	TAS Traceable Author Statement more info	PubMed
protein binding	IPI Inferred from Physical Interaction more info	PubMed
protein tyrosine kinase activator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
Fc-gamma receptor signaling pathway involved in phagocytosis	TAS Traceable Author Statement more info
actin polymerization or depolymerization	NAS Non-traceable Author Statement more info	PubMed
cellular component movement	IDA Inferred from Direct Assay more info	PubMed
innate immune response	TAS Traceable Author Statement more info
negative regulation of cell proliferation	TAS Traceable Author Statement more info	PubMed
peptidyl-tyrosine phosphorylation	IDA Inferred from Direct Assay more info	PubMed
somitogenesis	IEA Inferred from Electronic Annotation more info
transmembrane receptor protein tyrosine kinase signaling pathway	TAS Traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
cell junction	IEA Inferred from Electronic Annotation more info
cytoskeleton	IEA Inferred from Electronic Annotation more info
cytosol	TAS Traceable Author Statement more info
endoplasmic reticulum	TAS Traceable Author Statement more info	PubMed
filopodium	IDA Inferred from Direct Assay more info	PubMed
growth cone	IEA Inferred from Electronic Annotation more info
intracellular	IDA Inferred from Direct Assay more info	PubMed
lamellipodium	IDA Inferred from Direct Assay more info	PubMed
nucleus	IEA Inferred from Electronic Annotation more info
synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: abl interactor 1

Names: abl interactor 1; Abelson interactor 1; nap1 binding protein; abl-binding protein 4; interactor protein AblBP4; Abl-interactor protein 1 long; eps8 SH3 domain-binding protein; spectrin SH3 domain-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_030025.1 RefSeqGene

Range

5001..119492

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001012750.2 → NP_001012768.1 abl interactor 1 isoform b

Status: REVIEWED

Description

Transcript Variant: This variant (2) lacks an alternate in-frame coding exon, compared to variant 1. The resulting protein (isoform b) has the same N- and C-termini but is shorter compared to isoform a.

Source sequence(s)

AB040151, AF006516, AL390961, DB019974

Consensus CDS

CCDS31171.1

UniProtKB/Swiss-Prot

Q8IZP0

Conserved Domains (2) summary

cd11971
Location:423 – 481
Blast Score: 337

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 171
Blast Score: 339

Abi_HHR; Abl-interactor HHR
NM_001012751.2 → NP_001012769.1 abl interactor 1 isoform c

Status: REVIEWED

Description

Transcript Variant: This variant (3) lacks two alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform c) has the same N- and C-termini but is shorter compared to isoform a.

Source sequence(s)

AB040151, AL390961, DB019974

Consensus CDS

CCDS31170.1

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000365308, OTTHUMP00000019348, ENST00000376138, OTTHUMT00000047283

Conserved Domains (2) summary

cd11971
Location:394 – 452
Blast Score: 336

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 171
Blast Score: 338

Abi_HHR; Abl-interactor HHR
NM_001012752.2 → NP_001012770.1 abl interactor 1 isoform d

Status: REVIEWED

Description

Transcript Variant: This variant (4) lacks two alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform d) has the same N- and C-termini but is shorter compared to isoform a.

Source sequence(s)

AB040151, AL390961, BC024254, DB019974

Consensus CDS

CCDS31169.1

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000365309, OTTHUMP00000019355, ENST00000376139, OTTHUMT00000047291

Conserved Domains (2) summary

cd11971
Location:418 – 476
Blast Score: 337

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 166
Blast Score: 316

Abi_HHR; Abl-interactor HHR
NM_001178116.1 → NP_001171587.1 abl interactor 1 isoform e

Status: REVIEWED

Description

Transcript Variant: This variant (5) contains one alternate exon and lacks a different in-frame coding exon, compared to variant 1. The resulting protein (isoform e) has the same N- and C-termini but is shorter when it is compared to isoform a.

Source sequence(s)

AK126803, AL390961, DB019974

Consensus CDS

CCDS53501.1

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000279599, ENST00000346832

Conserved Domains (2) summary

pfam07815
Location:110 – 188
Blast Score: 342

Abi_HHR; Abl-interactor HHR

cd11971
Location:438 – 496
Blast Score: 338

SH3_Abi1; Src homology 3 domain of Abl Interactor 1
NM_001178119.1 → NP_001171590.1 abl interactor 1 isoform f

Status: REVIEWED

Description

Transcript Variant: This variant (6) lacks an alternate in-frame coding exon and uses a different splice site, compared to variant 1. The resulting protein (isoform f) has the same N- and C-termini but is shorter when it is compared to isoform a.

Source sequence(s)

AB040151, AF006516, AL390961, DB019974

Consensus CDS

CCDS53500.1

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000352114, OTTHUMP00000019354, ENST00000359188, OTTHUMT00000047289

Conserved Domains (2) summary

cd11971
Location:422 – 480
Blast Score: 333

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 171
Blast Score: 341

Abi_HHR; Abl-interactor HHR
NM_001178120.1 → NP_001171591.1 abl interactor 1 isoform g

Status: REVIEWED

Description

Transcript Variant: This variant (7) lacks two alternate in-frame coding exons and uses a different splice site, compared to variant 1. The resulting protein (isoform g) has the same N- and C-termini but is shorter when it is compared to isoform a.

Source sequence(s)

AB040151, AF001628, AL390961, DB019974

Consensus CDS

CCDS53499.1

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000365340, OTTHUMP00000019349, ENST00000376170, OTTHUMT00000047284

Conserved Domains (2) summary

cd11971
Location:393 – 451
Blast Score: 332

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 171
Blast Score: 340

Abi_HHR; Abl-interactor HHR
NM_001178121.1 → NP_001171592.1 abl interactor 1 isoform h

Status: REVIEWED

Description

Transcript Variant: This variant (8) lacks three alternate in-frame coding exons and uses a different splice site, compared to variant 1. The resulting protein (isoform h) has the same N- and C-termini but is shorter when it is compared to isoform a. This isoform has also been called the 'long' isoform.

Source sequence(s)

AB040151, AF260262, AK291823, AL390961, DB019974

Consensus CDS

CCDS53498.1

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000365336, OTTHUMP00000019350, ENST00000376166, OTTHUMT00000047285

Conserved Domains (2) summary

cd11971
Location:388 – 446
Blast Score: 332

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 166
Blast Score: 317

Abi_HHR; Abl-interactor HHR
NM_001178122.1 → NP_001171593.1 abl interactor 1 isoform i

Status: REVIEWED

Description

Transcript Variant: This variant (9) lacks two alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform i) has the same N- and C-termini but is shorter when it is compared to isoform a. This isoform has also been called 'variant 41'.

Source sequence(s)

AB040151, AL390961, DB019974, FJ380057

UniProtKB/TrEMBL

B6VEX3

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000365307, ENST00000376137

Conserved Domains (2) summary

cd11971
Location:364 – 422
Blast Score: 331

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 171
Blast Score: 342

Abi_HHR; Abl-interactor HHR
NM_001178123.1 → NP_001171594.1 abl interactor 1 isoform j

Status: REVIEWED

Description

Transcript Variant: This variant (10) lacks three alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform j) has the same N- and C-termini but is shorter when it is compared to isoform a. This isoform has also been called 'variant 21'.

Source sequence(s)

AB040151, AL390961, DB019974, FJ380058

UniProtKB/TrEMBL

B6VEX4

UniProtKB/Swiss-Prot

Q8IZP0

Conserved Domains (2) summary

cd11971
Location:335 – 393
Blast Score: 332

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 171
Blast Score: 340

Abi_HHR; Abl-interactor HHR
NM_001178124.1 → NP_001171595.1 abl interactor 1 isoform k

Status: REVIEWED

Description

Transcript Variant: This variant (11) lacks three alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform k) has the same N- and C-termini but is shorter when it is compared to isoform a. This isoform has also been called 'variant 72'.

Source sequence(s)

AB040151, AL390961, DB019974, FJ380059

UniProtKB/TrEMBL

B6VEX5

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000439646, ENST00000536334

Conserved Domains (2) summary

cd11971
Location:330 – 388
Blast Score: 332

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

pfam07815
Location:93 – 166
Blast Score: 317

Abi_HHR; Abl-interactor HHR
NM_001178125.1 → NP_001171596.1 abl interactor 1 isoform l

Status: REVIEWED

Description

Transcript Variant: This variant (12) lacks five alternate in-frame coding exons, compared to variant 1. The resulting protein (isoform l) has the same N- and C-termini but is shorter when it is compared to isoform a.

Source sequence(s)

AK298646, AL390961, DB019974

Consensus CDS

CCDS53497.1

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000440101, ENST00000490841

Conserved Domains (1) summary

cd11971
Location:271 – 329
Blast Score: 333

SH3_Abi1; Src homology 3 domain of Abl Interactor 1
NM_005470.3 → NP_005461.2 abl interactor 1 isoform a

Status: REVIEWED

Description

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform a).

Source sequence(s)

AB040151, AL390961, DB019974, U87166

Consensus CDS

CCDS7150.1

UniProtKB/Swiss-Prot

Q8IZP0

Related

ENSP00000365312, OTTHUMP00000019352, ENST00000376142, OTTHUMT00000047287

Conserved Domains (2) summary

pfam07815
Location:93 – 171
Blast Score: 340

Abi_HHR; Abl-interactor HHR

cd11971
Location:450 – 508
Blast Score: 336

SH3_Abi1; Src homology 3 domain of Abl Interactor 1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh37.p10 Primary Assembly

Genomic

NC_000010.10 Reference GRCh37.p10 Primary Assembly

Range

27035525..27150016, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate HuRef

Genomic

AC_000142.1 Alternate HuRef

Range

26695811..26810376, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.0

Genomic

NC_018921.1 Alternate CHM1_1.0

Range

26942089..27056715, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Nucleotide		Protein
Heading	Accession and Version	Protein
genomic	ABBA01034409.1 (34734..42442)	None
genomic	ABBA01034410.1	None
genomic	ABBA01034411.1	None
genomic	ABBA01034412.1	None
genomic	AJ277065.1	CAB88006.1
genomic	AL139404.9 (2000..78094)	None
genomic	AL390961.17 (135553..173949)	None
genomic	AMYH01002201.1 (111878..183442)	None
genomic	AMYH01002202.1	None
genomic	AMYH01002203.1	None
genomic	CH471072.2	EAW86077.1
		EAW86078.1
		EAW86079.1
		EAW86080.1
		EAW86081.1
		EAW86082.1
		EAW86083.1
mRNA	AB040151.1	BAB55675.1
mRNA	AB209268.1	BAD92505.1
mRNA	AF001628.1	AAD00897.1
mRNA	AF006516.1	AAB62569.1
mRNA	AF260262.1	AAF70309.1
mRNA	AF540955.1	AAN28379.1
mRNA	AK126803.1	BAG54374.1
mRNA	AK291823.1	BAF84512.1
mRNA	AK296751.1	BAG59334.1
mRNA	AK298646.1	BAG60820.1
mRNA	AK315914.1	BAH14285.1
mRNA	BC013238.1	None
mRNA	BC024254.2	AAH24254.1
mRNA	DB019974.1	None
mRNA	FJ380057.1	ACJ12783.1
mRNA	FJ380058.1	ACJ12784.1
mRNA	FJ380059.1	ACJ12785.1
mRNA	U87166.1	AAC39757.1