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FBXW8 F-box and WD repeat domain containing 8 [ Equus caballus (horse) ]

Gene ID: 100055213, updated on 8-Mar-2024

Summary

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Official Symbol
FBXW8provided by VGNC
Official Full Name
F-box and WD repeat domain containing 8provided by VGNC
Primary source
VGNC:VGNC:17969
See related
Ensembl:ENSECAG00000008712
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
13
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 8 NC_009151.3 (18743959..18884967, complement)
102 previous assembly EquCab2.0 (GCF_000002305.2) 8 NC_009151.2 (16334777..16449115, complement)

Chromosome 8 - NC_009151.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102148141 Neighboring gene nitric oxide synthase 1 Neighboring gene F-box protein 21 Neighboring gene uncharacterized LOC111774637 Neighboring gene uncharacterized LOC111774638 Neighboring gene tescalcin Neighboring gene uncharacterized LOC111774639 Neighboring gene harakiri, BCL2 interacting protein Neighboring gene ring finger protein, transmembrane 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cilium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of Cul7-RING ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in centriole IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ciliary basal body IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
F-box/WD repeat-containing protein 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009151.3 Reference EquCab3.0 Primary Assembly

    Range
    18743959..18884967 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023647075.1 → XP_023502843.1  F-box/WD repeat-containing protein 8 isoform X3

    Conserved Domains (3) summary
    sd00039
    Location:200 → 241
    7WD40; WD40 repeat [structural motif]
    pfam15736
    Location:378 → 510
    DUF4684; Domain of unknown function (DUF4684)
    cl25539
    Location:20 → 312
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_023647073.1 → XP_023502841.1  F-box/WD repeat-containing protein 8 isoform X1

    Conserved Domains (4) summary
    sd00039
    Location:386 → 427
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:115 → 157
    F-box-like
    pfam15736
    Location:564 → 696
    DUF4684; Domain of unknown function (DUF4684)
    cl25539
    Location:206 → 498
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_023647074.1 → XP_023502842.1  F-box/WD repeat-containing protein 8 isoform X2

    UniProtKB/TrEMBL
    A0A3Q2KV09
    Related
    ENSECAP00000028037.2, ENSECAT00000045853.3
    Conserved Domains (3) summary
    COG2319
    Location:260 → 561
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:386 → 427
    7WD40; WD40 repeat [structural motif]
    pfam12937
    Location:115 → 157
    F-box-like
Nucleotide Protein
Heading Accession and Version

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