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IARS1 isoleucyl-tRNA synthetase 1 [ Equus caballus (horse) ]

Gene ID: 100054721, updated on 8-Mar-2024

Summary

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Official Symbol
IARS1provided by VGNC
Official Full Name
isoleucyl-tRNA synthetase 1provided by VGNC
Primary source
VGNC:VGNC:18921
See related
Ensembl:ENSECAG00000023253
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus caballus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Also known as
IARS
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 23
Exon count:
35
Annotation release Status Assembly Chr Location
103 current EquCab3.0 (GCF_002863925.1) 23 NC_009166.3 (55265589..55341866)
102 previous assembly EquCab2.0 (GCF_000002305.2) 23 NC_009166.2 (55437428..55513744)

Chromosome 23 - NC_009166.3Genomic Context describing neighboring genes Neighboring gene centromere protein P Neighboring gene osteoglycin Neighboring gene uncharacterized LOC111770234 Neighboring gene small nucleolar RNA SNORA84 Neighboring gene nucleolar protein 8 Neighboring gene uncharacterized LOC102149850 Neighboring gene zinc finger protein 484 Neighboring gene major facilitator superfamily domain containing 14B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Annotation of the Protein Coding Regions of the Equine Genome. Hestand MS, et al. PLoS One, 2015. PMID 26107351, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables aminoacyl-tRNA editing activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables isoleucine-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tRNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in isoleucyl-tRNA aminoacylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
isoleucine--tRNA ligase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus caballus Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EquCab3.0 Primary Assembly

Genomic

  1. NC_009166.3 Reference EquCab3.0 Primary Assembly

    Range
    55265589..55341866
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023627620.1 → XP_023483388.1  isoleucine--tRNA ligase, cytoplasmic isoform X1

    UniProtKB/TrEMBL
    A0A5F5PJP7, A0A5F5PQ67
    Related
    ENSECAP00000050381.2, ENSECAT00000068788.2
    Conserved Domains (1) summary
    cl26128
    Location:6 → 1133
    tRNA-synt_1g; tRNA synthetases class I (M)

  2. XM_001491121.6 → XP_001491171.2  isoleucine--tRNA ligase, cytoplasmic isoform X2

    UniProtKB/TrEMBL
    A0A5F5PJP7
    Related
    ENSECAP00000048508.1, ENSECAT00000077214.2
    Conserved Domains (3) summary
    cd07961
    Location:640 → 833
    Anticodon_Ia_Ile_ABEc; Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases
    cd00818
    Location:39 → 640
    IleRS_core; catalytic core domain of isoleucyl-tRNA synthetases
    PLN02882
    Location:6 → 1071
    PLN02882; aminoacyl-tRNA ligase
Nucleotide Protein
Heading Accession and Version

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