GLS2 glutaminase 2 (liver, mitochondrial) [Monodelphis domestica (gray short-tailed opossum)] - Gene

Summary

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Gene symbol: GLS2
Gene description: glutaminase 2 (liver, mitochondrial)
Gene type: protein coding
RefSeq status: MODEL
Organism: Monodelphis domestica
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis

Genomic context

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Location :: chromosome: 8

Sequence :: Chromosome: 8; NC_008808.1 (31315014..31325253, complement)

See GLS2 in MapViewer

Chromosome 8 - NC_008808.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

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Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

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Pathways from BioSystems

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Alanine, aspartate and glutamate metabolism, organism-specific biosystem (from KEGG)
Alanine, aspartate and glutamate metabolism, organism-specific biosystem
Alanine, aspartate and glutamate metabolism
Alanine, aspartate and glutamate metabolism, conserved biosystem (from KEGG)
Alanine, aspartate and glutamate metabolism, conserved biosystem
Alanine, aspartate and glutamate metabolism
Arginine and proline metabolism, organism-specific biosystem (from KEGG)
Arginine and proline metabolism, organism-specific biosystem
Arginine and proline metabolism
Arginine and proline metabolism, conserved biosystem (from KEGG)
Arginine and proline metabolism, conserved biosystem
Arginine and proline metabolism
D-Glutamine and D-glutamate metabolism, organism-specific biosystem (from KEGG)
D-Glutamine and D-glutamate metabolism, organism-specific biosystem
D-Glutamine and D-glutamate metabolism
D-Glutamine and D-glutamate metabolism, conserved biosystem (from KEGG)
D-Glutamine and D-glutamate metabolism, conserved biosystem
D-Glutamine and D-glutamate metabolism
GABAergic synapse, organism-specific biosystem (from KEGG)
GABAergic synapse, organism-specific biosystemGamma aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the mammalian central nervous system (CNS). When released in the synaptic cleft, GABA binds to three major classes o...
GABAergic synapse, conserved biosystem (from KEGG)
GABAergic synapse, conserved biosystemGamma aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the mammalian central nervous system (CNS). When released in the synaptic cleft, GABA binds to three major classes o...
Glutamatergic synapse, organism-specific biosystem (from KEGG)
Glutamatergic synapse, organism-specific biosystemGlutamate is the major excitatory neurotransmitter in the mammalian central nervous system(CNS). Glutamate is packaged into synaptic vesicles in the presynaptic terminal. Once released into the synap...
Glutamatergic synapse, conserved biosystem (from KEGG)
Glutamatergic synapse, conserved biosystemGlutamate is the major excitatory neurotransmitter in the mammalian central nervous system(CNS). Glutamate is packaged into synaptic vesicles in the presynaptic terminal. Once released into the synap...
Proximal tubule bicarbonate reclamation, organism-specific biosystem (from KEGG)
Proximal tubule bicarbonate reclamation, organism-specific biosystemOne of the major tasks of the renal proximal tubule (PT) is to secrete acid into the tubule lumen, thereby reabsorbing approximately 80% of the filtered bicarbonate (HCO3(-)), as well as generating "...
Proximal tubule bicarbonate reclamation, conserved biosystem (from KEGG)
Proximal tubule bicarbonate reclamation, conserved biosystemOne of the major tasks of the renal proximal tubule (PT) is to secrete acid into the tubule lumen, thereby reabsorbing approximately 80% of the filtered bicarbonate (HCO3(-)), as well as generating "...

General gene information

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Homology

OrthoDB: The Hierarchical Catalog of Eukaryotic Orthologs

General protein information

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Names: glutaminase 2 (liver, mitochondrial)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Build 2.2

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MonDom5 Primary Assembly

Genomic

NC_008808.1

Range

31315014..31325253, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001375574.2 → XP_001375611.2

Conserved Domains (3) summary

cd00204
Location:539 – 632
Blast Score: 171

ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...

pfam04960
Location:226 – 512
Blast Score: 1244

Glutaminase; Glutaminase

pfam12796
Location:539 – 632
Blast Score: 177

Ank_2; Ankyrin repeats (3 copies)