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CFTR CF transmembrane conductance regulator [ Monodelphis domestica (gray short-tailed opossum) ]

Gene ID: 100014119, updated on 8-Mar-2024

Summary

Gene symbol
CFTR
Gene description
CF transmembrane conductance regulator
See related
Ensembl:ENSMODG00000015771
Gene type
protein coding
RefSeq status
MODEL
Organism
Monodelphis domestica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis
Orthologs
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Genomic context

See CFTR in Genome Data Viewer
Location:
chromosome: 5
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2023_05 current mMonDom1.pri (GCF_027887165.1) 5 NC_077231.1 (185352822..185557657)
103 previous assembly MonDom5 (GCF_000002295.2) 8 NC_008808.1 (173124897..173329502)

Chromosome 5 - NC_077231.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene Wnt family member 2 Neighboring gene ankyrin repeat, SAM and basic leucine zipper domain containing 1 Neighboring gene cortactin binding protein 2 Neighboring gene uncharacterized LOC107650128 Neighboring gene iron-sulfur cluster assembly enzyme ISCU-like

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ABC-type transporter activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables chloride channel activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in bicarbonate transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cystic fibrosis transmembrane conductance regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027887165.1-RS_2023_05

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mMonDom1.pri

Genomic

  1. NC_077231.1 Reference mMonDom1.pri

    Range
    185352822..185557657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_056799582.1XP_056655560.1  cystic fibrosis transmembrane conductance regulator

    UniProtKB/TrEMBL
    F6ZS67