These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
Genomic
-
NG_023254.1 RefSeqGene
- Range
- 5001..169691
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001032998.1 → NP_001028170.1 kynureninase isoform b
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR, 3' UTR and coding region compared to variant 3. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a.
- Source sequence(s)
-
AL548658, BC000879
- Consensus CDS
-
CCDS33299.1
- UniProtKB/Swiss-Prot
-
Q16719
- Related
- ENSP00000364928, OTTHUMP00000204305, ENST00000375773, OTTHUMT00000332171
- Conserved Domains (1) summary
-
- cl00321
Location:24 – 306
Blast Score: 476
- AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
-
NM_001199241.1 → NP_001186170.1 kynureninase isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) represents the longest transcript variant. Variants 1 and 3 encode isoform a.
- Source sequence(s)
-
AC013437, AK315343, AW290980, CB151988
- Consensus CDS
-
CCDS2183.1
- UniProtKB/Swiss-Prot
-
Q16719
- Related
- ENSP00000386731, OTTHUMP00000204304, ENST00000409512, OTTHUMT00000332170
- Conserved Domains (2) summary
-
- TIGR01814
Location:30 – 459
Blast Score: 1659
- kynureninase; kynureninase
- cl00321
Location:24 – 462
Blast Score: 772
- AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
-
NM_003937.2 → NP_003928.1 kynureninase isoform a
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) differs in the 5'UTR compared to variant 3.
- Source sequence(s)
-
AL548658, AW296221, U57721
- Consensus CDS
-
CCDS2183.1
- UniProtKB/Swiss-Prot
-
Q16719
- Related
- ENSP00000264170, OTTHUMP00000162647, ENST00000264170, OTTHUMT00000254772
- Conserved Domains (2) summary
-
- TIGR01814
Location:30 – 459
Blast Score: 1659
- kynureninase; kynureninase
- cl00321
Location:24 – 462
Blast Score: 772
- AAT_I; Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000002.11 Reference GRCh37.p5 Primary Assembly
- Range
- 143635195..143799885
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000134.1 Alternate HuRef
- Range
- 135626307..135791074
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)